liposome

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liposome

 [lip´o-sōm]
a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

lip·o·some

(lip'ō-sōm),
1. A spheric particle of lipid substance suspended in an aqueous medium within a tissue.
2. Any small, roughly spheric artificial vesicle consisting of a lipid bilayer enclosing some of the suspending medium.
[lipo- + G. sōma, body]
Farlex Partner Medical Dictionary © Farlex 2012

liposome

(lĭp′ə-sōm′, lī′pə-)
n.
A microscopic artificial vesicle consisting of an aqueous core enclosed in phospholipid molecules, used to convey vaccines, drugs, or other substances to target tissues.

lip′o·so′mal adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

liposome

Lipid vesicle Drug delivery A synthetic, uniform bilayer lipid membrane-bound vesicle formed by emulsification of cell membranes in dilute salt solutions, which is used to deliver toxic drugs–eg, amphotericin B, doxorubicin, pentavalent antimony–tagging them with an organ-specific antibody. See Liposome-encapsulated amphotericin B, Stealth liposome.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

liposome

an artificially constructed PHOSPHOLIPID VESICLE, which can be used in various biological experiments. Certain drugs may be incorporated into liposomes in order to administer them. In this way the drugs may be protected from degradation and may not exert general toxicity when introduced into the bloodstream.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Liposome

Fat molecule made up of layers of lipids.
Mentioned in: Gene Therapy
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The drivers for liposomal doxorubicin market include rise in ovarian and breast cancer coupled with increasing awareness for liposomal doxorubicin formulation.
So far, there was no agreed approach to the naming of medicines containing liposomal or pegylated liposomal formulations.
"Cytori Nanomedicine is focused on the liposomal encapsulation of anti-neoplastic chemotherapy agents, which may enable the effective delivery of the agents to target sites while reducing systemic toxicity.
The researchers found that the median pain score with movement at 48 hours postoperatively was 4 (in an 11-point scale) in the liposomal bupivacaine group and 3.5 in the placebo group (P = 0.72).
Although liposomes developed for parenteral administration have been used therapeutically for many years, the number of liposomal drugs for ocular and intraocular administration have passed from R&D to clinical trial for ocular and intraocular applications is rather limited.
Liposomal amphotericin B can be given for a longer period and at higher doses in immunocompromised patients to prevent recurrence of kala-azar.
Because of costs, we currently are restricted to using liposomal bupivacaine in our robotic surgeries only.
Because of its severe nephrotoxicity conventional amphotericin B has been superseded by liposomal formulations in advance and affluent countries however liposomal formulations of amphotericin B are very expensive7.
Celator's lead product is VYXEOS (also known as CPX-351), a nano-scale liposomal formulation of cytarabine: daunorubicin that has completed a Phase 3 trial for the treatment of acute myeloid leukemia.
There are several liposomal formulations of anticancer drugs authorized by United State Food and Drug Administration including doxorubicin.
During the trial, patients were randomised to one of six treatment units (paclitaxel, topotecan or pegylated liposomal doxorubicin with or without Avastin).
INTRODUCTION:The signal of second harmonic generation (SHG) comes from interaction between light and polarized water close to the lipid of liposomal surfaces.