liposome

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liposome

 [lip´o-sōm]
a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

lip·o·some

(lip'ō-sōm),
1. A spheric particle of lipid substance suspended in an aqueous medium within a tissue.
2. Any small, roughly spheric artificial vesicle consisting of a lipid bilayer enclosing some of the suspending medium.
[lipo- + G. sōma, body]

liposome

/lipo·some/ (lip´o-sōm) a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

liposome

(lĭp′ə-sōm′, lī′pə-)
n.
A microscopic artificial vesicle consisting of an aqueous core enclosed in phospholipid molecules, used to convey vaccines, drugs, or other substances to target tissues.

lip′o·so′mal adj.

liposome

[lip′əsōm]
Etymology: Gk, lipos, fat, soma, body
a small, spheric particle consisting of a bilayer of phospholipid molecules surrounding an aqueous solution.

liposome

Lipid vesicle Drug delivery A synthetic, uniform bilayer lipid membrane-bound vesicle formed by emulsification of cell membranes in dilute salt solutions, which is used to deliver toxic drugs–eg, amphotericin B, doxorubicin, pentavalent antimony–tagging them with an organ-specific antibody. See Liposome-encapsulated amphotericin B, Stealth liposome.

liposome

an artificially constructed PHOSPHOLIPID VESICLE, which can be used in various biological experiments. Certain drugs may be incorporated into liposomes in order to administer them. In this way the drugs may be protected from degradation and may not exert general toxicity when introduced into the bloodstream.

Liposome

Fat molecule made up of layers of lipids.
Mentioned in: Gene Therapy

liposome

a spherical structure, usually multilamelate, prepared from eukaryotic cell membranes which may be used as a carrier for glycoprotein antigens and drugs.
References in periodicals archive ?
Liposomal Doxorubicin SUN contains a liposome coated with sodium methoxy PEG-40-carbonyl-DPSE.
We used dynamic light scattering (DLS) for find the size of liposomal structure.
As previously reported, since the safety profile of Liposomal Grb-2 is quite favorable, the Company expanded the protocol for its Phase I clinical trial to evaluate higher doses of Liposomal Grb-2 than originally planned.
Well, until recently there haven't been any studies on liposomal glutathione.
We postulate that biodegradation of the liposomal vehicle may lead to interference due to light scatter or precipitation that affects the absorbance measurements.
There were no fungal infections after a mean of 9 months in the 40 patients who began the liposomal drug de novo after lung transplant.
The firm has commenced enrolment into Cohort eight that will complete the Phase Ib study of Liposomal Grb-2.
The company's major focus is developing antibiotic therapy delivered via next-generation liposomal technology in areas of high unmet need in respiratory disease.
Four of the five studies compared liposomal lidocaine with EMLA, the most commonly used method to reduce pain from dermatologic procedures.
The potential of Liposomal Grb-2 as a frontline treatment for triple negative breast cancer and inflammatory breast cancer is a major new development for Bio-Path that has the opportunity to produce substantial value for the Company.
This segment of the safety study will evaluate two doses (60 mg/m2 and 90 mg/m2) of the company's Liposomal Grb-2 in combination with Ara-C front line therapy.
M2 PHARMA-February 10, 2015-Bio-Path Holdings moves Liposomal Grb-2 into the next phase of clinical development in AML patients