liposome

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Related to liposomal: liposomal doxorubicin, liposomal amphotericin B

liposome

 [lip´o-sōm]
a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

lip·o·some

(lip'ō-sōm),
1. A spheric particle of lipid substance suspended in an aqueous medium within a tissue.
2. Any small, roughly spheric artificial vesicle consisting of a lipid bilayer enclosing some of the suspending medium.
[lipo- + G. sōma, body]

liposome

/lipo·some/ (lip´o-sōm) a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

liposome

(lĭp′ə-sōm′, lī′pə-)
n.
A microscopic artificial vesicle consisting of an aqueous core enclosed in phospholipid molecules, used to convey vaccines, drugs, or other substances to target tissues.

lip′o·so′mal adj.

liposome

[lip′əsōm]
Etymology: Gk, lipos, fat, soma, body
a small, spheric particle consisting of a bilayer of phospholipid molecules surrounding an aqueous solution.

liposome

Lipid vesicle Drug delivery A synthetic, uniform bilayer lipid membrane-bound vesicle formed by emulsification of cell membranes in dilute salt solutions, which is used to deliver toxic drugs–eg, amphotericin B, doxorubicin, pentavalent antimony–tagging them with an organ-specific antibody. See Liposome-encapsulated amphotericin B, Stealth liposome.

liposome

an artificially constructed PHOSPHOLIPID VESICLE, which can be used in various biological experiments. Certain drugs may be incorporated into liposomes in order to administer them. In this way the drugs may be protected from degradation and may not exert general toxicity when introduced into the bloodstream.

Liposome

Fat molecule made up of layers of lipids.
Mentioned in: Gene Therapy

liposome

a spherical structure, usually multilamelate, prepared from eukaryotic cell membranes which may be used as a carrier for glycoprotein antigens and drugs.
References in periodicals archive ?
Having brought dozens of successful liquid liposomal formulations to the market and been recognized by the industry for innovation, Dr.
As previously reported, since the safety profile of Liposomal Grb-2 is quite favorable, the Company expanded the protocol for its Phase I clinical trial to evaluate higher doses of Liposomal Grb-2 than originally planned.
Well, until recently there haven't been any studies on liposomal glutathione.
We postulate that biodegradation of the liposomal vehicle may lead to interference due to light scatter or precipitation that affects the absorbance measurements.
There were no fungal infections after a mean of 9 months in the 40 patients who began the liposomal drug de novo after lung transplant.
Their patented Liposomal Absorption Technology has given them the reputation of developing the most absorbable vitamins and supplements in the market.
Liposomal lidocaine proved superior to placebo and equal to or better than EMLA in eliminating pain.
Offering health products with the highest absorption rates, MaxHealthLabs is a leader in liposomal development.
Another positive development is the fact that one patient from Cohort 3 is continuing treatment with Liposomal Grb-2, and is currently in a fourth treatment cycle.
The vitamin C, as well as the glutathione liposomal product, is in liquid form.
Separately, Bio-Path provided an update on clinical development of Liposomal Grb-2 announcing its intent to conduct three Phase II clinical trials of Liposomal Grb-2 salvage therapy in combination with frontline therapy in three different leukemia disease types.