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Any complex of fats with protein. A conjugated protein consisting of a simple protein combined with a fat (lipid) group. The blood lipoproteins, which are the cholesterol carriers of the body, are classified by density, in accordance with the proportions of protein, as very low density (VLDL), low density (LDL) and high density (HDL). LDLs contain relatively large amounts of cholesterol. HDLs contain 50% of protein and only 20% of cholesterol. LDLs transport lipids to muscles and to fat stores and are associated with the arterial disease ATHEROSCLEROSIS and thus heart disease and STROKE. HDLs are protective against these diseases because their main role is to transport cholesterol from the periphery back to the liver. They also carry paraoxanase enzymes that limit oxidative modification of LDLs necessary before cholesterol can be laid down in arterial walls. Blood concentration of HDL cholesterol shows a strong inverse correlation with the risk of coronary heart disease.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


The packages in which cholesterol and triglycerides travel throughout the body.
Mentioned in: Lipoproteins Test
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

Patient discussion about lipoproteins

Q. what are the sources for high density lipoprotein? I have heard that high density lipoprotein is good for heart. What differences does it make in heart’s health and what are the sources for high density lipoprotein?

A. Hi Liam, it is very important that we have high density lipoprotein (HDL) in our body. The fact is that the HDL is formed inside the body. They are known as good cholesterol as they are famous for their protection for heart against the heart diseases. It has been found that Vitamin B3 or Niacin consumption increases the count of HDL. It’s good to cut on the diet having more of saturated fats and oils, which increases the chances of heart attack.

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References in periodicals archive ?
Methods: The expression of tissue factor and lectin-like oxidised low density lipoprotein receptor was detected using Western blot methods.
Lipoprotein lipase (LPL) is a glycoprotein mainly synthesized in the adipose and muscle cells which catalyzes the hydrolysis of triacylglycerol in chylomicrrons and very low density lipoprotein.
Beneficial effects of designed dietary fatty acid compositions on lipids in triacylglycerol-rich lipoproteins among Chinese patients with type 2 diabetes mellitus.
The HDL lipoprotein is commonly known as "the good" cholesterol, although the health effects of HDL particles actually are dependent on their size and composition.
Lipoproteins are spherical particles comprising a core of triglycerides and cholesterol esters (CEs), and a surface of phospholipid and unesterified cholesterol (UC) in which apoproteins reside.
Based on samples from 912 MI, 1,146 IS, and 1,138 ICH cases, as well as 1,466 common control subjects, the researchers found that very low-, intermediate-, and low-density lipoprotein particles were positively associated with MI and IS.
In these studies the exchange between palm olein and olive oil resulted in similar plasma and lipoprotein cholesterol values (total cholesterol, TC, low-density lipoprotein cholesterol, LDL-C and high density lipoprotein cholesterol, HDL-C).
The regulatory role of apoE and apoC-III lipoproteins in the apoB metabolism was studied in a recent work on healthy subjects and patients with hypertriglyceridemia [50].
Lipoprotein lipase (LPL) plays a crucial role in the metabolism and transport of lipids.
The failure to suppress FFA in the postprandial period, due to the decreased activity of lipoprotein lipase (LPL), and the rise in plasma FFA due to increased adipocyte lipolysis are key mechanisms behind the increased hepatic very low density lipoproteins (VLDL)-TG secretion.
"The effect of 8 weeks of aerobic training on serum lipoproteins in non-athletic girls", European Journal of Experimental Biology, 4(1): 358-360.