lipoprotein lipase


Also found in: Dictionary, Thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to lipoprotein lipase: Lipoprotein lipase deficiency

lip·o·pro·tein li·pase

(lip'ō-prō'tēn lī'pās, lī'pō-),
An enzyme that hydrolyzes one fatty acid from a triacylglycerol; its activity is enhanced by heparin and inactivated by heparinase. It is activated by apolipoprotein C-II; a deficiency of lipoprotein lipase is associated with familial hyperlipoproteinemia type I.
See also: familial lipoprotein lipase inhibitor, clearing factors.

lip·o·pro·tein li·pase

(lip'ō-prō'tēn lip'ās)
An enzyme that hydrolyzes one fatty acid from a triacylglycerol; its activity is enhanced by heparin and inactivated by heparinase.
See also: clearing factors
References in periodicals archive ?
Association of lipoprotein lipase Hind III and Ser 447 Ter polymorphisms with dyslipidemia in Asian Indians.
Comparative studies of vertebrate lipoprotein lipase: a key enzyme of very low density lipoprotein metabolism.
Effects of hyperinsulinemia on lipoprotein lipase, angiopoietin-like protein 4, and glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 in subjects with and without type 2 diabetes mellitus.
Interestingly, it was found earlier that IFN[gamma] is involved in lipoprotein lipase inhibition, at the level of LPL gene transcription [19].
Mabuchi et al., "Association of angiopoietin-like protein 3 with hepatic triglyceride lipase and lipoprotein lipase activities in human plasma," Annals of Clinical Biochemistry, vol.
Kersten, "Regulation of lipoprotein lipase by Angptl4," Trends in Endocrinology and Metabolism, vol.
Eckel, "Lipoprotein lipase: from gene to obesity," The American Journal of Physiology--Endocrinology and Metabolism, vol.
The exon 8 of LPL gene is the key sequence for coding the catalytic center of lipoprotein lipase (Li et al., 2014).
Lipoprotein lipase (LPL) catalyzes triglycerides (TG) hydrolysis from circulating chylomicrons and very low-density lipoproteins (VLDL), producing chol esterol rich lipoprotein remnants and components of high-density lipoprotein (HDL).
Another curative drug is Glybera, which treats patients deficient in lipoprotein lipase, a protein needed to break down fat molecules.
First, diminished activity of lipoprotein lipase (LPL) may result in the excessive transfer of TGs from triglyceride-rich chylomicrons and VLDL-c particles in exchange for cholesterol esters from HDL-c particles, thus reducing the levels of HDL-c.

Full browser ?