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1. a molecule in which lipids and polysaccharides are linked.
2. a major component of the cell wall of gram-negative bacteria; lipopolysaccharides are endotoxins and important antigens.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

lip·o·pol·y·sac·cha·ride (LPS),

1. A compound or complex of lipid and carbohydrate.
2. The lipopolysaccharide (endotoxin) released from the cell walls of gram-negative organisms that produces septic shock.
Farlex Partner Medical Dictionary © Farlex 2012


(lĭp′ō-pŏl′ē-săk′ə-rīd′, lī′pō-)
Any of a group of polysaccharides in which a lipid constitutes a portion of the molecule, found in the outer cell wall of gram-negative bacteria.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


A compound or complex of lipid and carbohydrate; the lipopolysaccharide (endotoxin) that is released from the cell walls of gram-negative organisms that produces septic shock.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Structure analysis of the lipopolysaccharide of Pasteurella multocida strains VP161: identification of both Kdo-P and kdo- Kdo species in the lipopolysaccharide.
Lipopolysaccharide associates with pro-atherogenic lipoproteins in periodontitis patients.
characterization of a virulence-associated epitope on the lipopolysaccharide of Legionella pneumophila serogroup 1", Epidemiol Infect 1995; 115:71-78.
Bacterial lipopolysaccharide-mediated fetal death: production of a newly recognized form of inducible cyclooxygenase (COX-2) in murine decidua in response to lipopolysaccharide. Journal of Clinical Investigation., 95: 725-731.
Lipopolysaccharide exposure decreases parthenogenetic development of bovine oocytes
Control group: mice were given saline; LPS group: mice were given lipopolysaccharide (LPS); EGCG group: mice were given epigallocatechin-3-gallate.
(18) They then treated the mice with either metformin alone, or metformin following injections of lipopolysaccharides to produce high-grade inflammation.
Lipopolysaccharide and D-galactosamine-induced hepatic injury is mediated by TNF-[alpha] and not by Fas ligand.
KEYWORDS: Hypertrophic Scar, Fibroblast Cell, Lipopolysaccharide, Mitogen-Activated Protein Kinase.
Gram-negative bacteria express one of six types of endotoxin or lipopolysaccharide (LPS), which can potentially induce life threatening pyrogenic reactions depending on the detailed molecular structure of LPS isoforms.
In the majority of Gram-negative bacteria, this outer membrane is an asymmetric bilayer with phospholipids on the inner leaflet and lipopolysaccharide (LPS) on the outer leaflet [1, 2].
For instance, all gram-negative bacteria have lipopolysaccharides (LPS); therefore, the lipopolysaccharide pattern recognition receptor of the host (e.g., TLR4) can detect the presence of virtually any gram-negative bacterial infection [4].