lipooxygenase


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lipooxygenase

, lipoxygenase (lip-ooks'ĭ-jen-ās, lip-oks'ĭ-jen-ās),
Any of a family of enzymes that convert unsaturated fatty acids to peroxides; important in the synthesis of leukotrienes from arachidonic acid.
[lipo- + oxygen + -ase]

lip·o·ox·y·gen·ase

, lipoxygenase (lipō-oksi-jĕ-nās, li-poks)
An enzyme that converts unsaturated fatty acids to peroxides acid.
[lipo- + oxygen + -ase]
References in periodicals archive ?
Inhibit phospholipase A2, cyclooxygenase and lipooxygenase pathways [right arrow] limit arachidonic acid release, including TXAs.
As such, the antinociceptive activity exhibited by crude methanolic extract of the leaves of Allium sativum may be due to the extract's ability to block any further expression of prostaglandins, which may be mediated through inhibition of cyclooxygenase and/or lipooxygenase activities.
Esculin (6,7-dihydroxy-6-0-glucosylcoumarin) is a glycosylated coumarin derivative promptly hydrolysed to produce its metabolite, esculetin, which is recognised as one the most antioxidant coumarins and most potent lipooxygenase and cyclooxygenase inhibitor (Li et al.
It has an important role in modulation of phospholipase, lipooxygenase, and cyclo-oxygenase with major effects on the expression of inflammation.
As such, the antinociceptive activity exhibited by crude methanolic extract of the leaves may be due to the extract's ability to block further expression of prostaglandins, which can be mediated through inhibition of cyclooxygenase and/or lipooxygenase activities.
As such, the antinociceptive activity exhibited by Cleng Marem may be due to the formulation's ability to block any further expression of prostaglandins, which may be mediated through inhibition of cyclooxygenase and/or lipooxygenase activities.
All the compounds tested--celecoxib (Celebrex[R]), aspirin, and ECE--slowed down the lipooxygenase (LOX) system, showing significant inhibition of PGE2 generation.
As such, the antinociceptive activity exhibited by crude methanolic extract of the leaves of Ziziphus mauritiana and Centella asiatica may be due to the extract's ability to block any further expression of prostaglandins, which may be mediated through inhibition of cyclooxygenase and/or lipooxygenase activities.
Inhibitory effects of cucurmin on in vitro lipooxygenase and cyclooxygenase activities in mouse epidermis.
As such, the antinociceptive activity exhibited by crude methanolic extract of the fruits may be due to the extract's ability to inhibit further expression of prostaglandins, which may in turn be mediated through inhibition of cyclooxygenase and/or lipooxygenase activities, because these enzymes are responsible for biosynthesis of prostaglandins.
As such, the antinociceptive activity exhibited by crude methanolic extract of the stems may be due to the extract's ability to inhibit further expression of prostaglandins, which may in turn be mediated through inhibition of cyclooxygenase and/or lipooxygenase activities.
Products produced by the metabolism include both cyclooxygenase products (prostaglandins, thromboxanes) and lipooxygenase products (leukotrienes).