Thickening and red discoloration of the skin as a result of diminished blood flow, usually caused by local or regional venous obstruction.


induration, hemosiderosis and inflammation, with excessive sclerosis of superficial tissues, characteristic of chronic venous stasis (see Box 1)
Box 1: Clinical features of chronic venous stasis of the lower limb
  • Pain (a ‘bursting’ sensation) on standing, relieved by elevation

  • Pitting oedema, gradually becoming woody oedema, in association with chronic inflammation

  • Cyanosis

  • Lipodermatosclerosis (chronic tissue fibrosis) and formation of ‘inverted champagne bottle leg’

  • Reduced ankle joint movement

  • Atrophie blanche (pre-ulcer sites)

  • Telangiectasia (dilated capillaries)

  • Varicosed (dilated and tortuous superficial) veins

  • Ulceration (lower one-third of leg)

  • Lichenification and skin scaling

  • Dermatitis/varicose eczema

  • Haemosiderosis

References in periodicals archive ?
There is hypertrophy of overlying epidermis giving polypoid appearance, known as lipodermatosclerosis.
The examination of the leg should include palpation of pulses and a search for the signs of venous hypertension, including varicose veins, hemosiderin pigmentation, varicose eczema, atrophie blanche, and lipodermatosclerosis.
Precapillary fibrin has been found in the dermis of almost all patients with the pre-ulcerative condition of lipodermatosclerosis (pigmentation, inflammation and induration of the skin).
2]), mucous-cutaneous pallor, abdomino-thoracic collateral circulation (Figure 1), giant hematoma in the right popliteal region extending to the level of the inferior half of the calf and the inferior third of the thigh (approximately 21/9 cm), lipodermatosclerosis of the inferior members, walk with unilateral support, due to the functional impotence of the right inferior limb, emphysematous thorax, Sp[O.
A VLU biopsy was performed in a total of 45 patients who had not used antibiotics and presented signs of CVI, such as edema, varicose veins, hyperpigmentation, and lipodermatosclerosis (Fig.
Venous-related skin changes may also develop, including hyperpigmentation in the perimalleolar region secondary to haemosiderin deposition, lipodermatosclerosis with scarring, thickening of the skin secondary to fibrosis in the dermis and subcutaneous fatty tissue, and atrophie blanche characterised by circular whitish and atrophic skin surrounded by dilated capillaries and hyperpigmentation.
Consequently, prolonged venous hypertension can induce circulatory changes that may result in hyperpigmentation, lipodermatosclerosis, and even ulceration.
Additionally the patient had bilateral, prominent varicose tracts with edema, eczema, hyperpigmentation and lipodermatosclerosis of both ankles, reflective of a severe peripheral vascular disease.
Lipodermatosclerosis occurs due to inflammation, necrosis and fibrosis of subcutaneous fat and the dermis.
8) The typical clinical presentation consists of swelling, discomfort, pain, venous claudication, hyperpigmentation, stasis dermatitis venous eczema, induration, lipodermatosclerosis, varicose veins and ultimately venous ulceration (Fig.
Lipodermatosclerosis is one condition that physicians often fat to think of as a scleroderma mimic.