Thickening and red discoloration of the skin as a result of diminished blood flow, usually caused by local or regional venous obstruction.


induration, hemosiderosis and inflammation, with excessive sclerosis of superficial tissues, characteristic of chronic venous stasis (see Box 1)
Box 1: Clinical features of chronic venous stasis of the lower limb
  • Pain (a 'bursting' sensation) on standing, relieved by elevation

  • Pitting oedema, gradually becoming woody oedema, in association with chronic inflammation

  • Cyanosis

  • Lipodermatosclerosis (chronic tissue fibrosis) and formation of 'inverted champagne bottle leg'

  • Reduced ankle joint movement

  • Atrophie blanche (pre-ulcer sites)

  • Telangiectasia (dilated capillaries)

  • Varicosed (dilated and tortuous superficial) veins

  • Ulceration (lower one-third of leg)

  • Lichenification and skin scaling

  • Dermatitis/varicose eczema

  • Haemosiderosis

References in periodicals archive ?
Venous-related skin changes may also develop, including hyperpigmentation in the perimalleolar region secondary to haemosiderin deposition, lipodermatosclerosis with scarring, thickening of the skin secondary to fibrosis in the dermis and subcutaneous fatty tissue, and atrophie blanche characterised by circular whitish and atrophic skin surrounded by dilated capillaries and hyperpigmentation.
Lipodermatosclerosis occurs due to inflammation, necrosis and fibrosis of subcutaneous fat and the dermis.
8) The typical clinical presentation consists of swelling, discomfort, pain, venous claudication, hyperpigmentation, stasis dermatitis venous eczema, induration, lipodermatosclerosis, varicose veins and ultimately venous ulceration (Fig.
And that group of patients has included 66 patients with active leg ulcers, unstable healed ulcers, or disabling lipodermatosclerosis.