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Among the differential diagnosis are lipoma, lipoblastoma, fibromatosis, cystic hygroma and pilomatrixoma.
Those in which adipose tissue predominates are distinguished from fibrolipoma by foci of immature mesenchyme and from lipoblastoma by their lack of a capsule and of a lobular pattern [2].
Lipoblastoma is a rare tumor composed of fetalembryonal fat that occurs exclusively in infants and children.
Plain radiography in patients with lipoblastoma generally shows a nonspecific soft tissue mass.
Two young girls with lipoblastoma and a review of the literature Pediatr Dermatol 2006; 23: 152-156.
First described by Jaffe, (2) a lipoblastoma is a developmental anomaly characterized by continued proliferation of lipoblasts in the postnatal period.
This variety of lipoblastoma has been termed lipoblastomatosis.
Lipomas, lipomatosis, angiolipomas, chondroid lipomas, lipoblastoma, lipobalostomatosis, spindle cell lipoma and pleomorphic lipomas are lesions that can mimic the condition.
Lipoblastoma is a rare benign tumor that occurs primarily in children younger than 3 years of age.
Site Telepathology 1 Cervix (biopsy) Undifferentiated carcinoma 2 Cervix (biopsy) Invasive SCC G3 (necrotic biopsy) 3 Cervix (biopsy) CIN3 4 Cervix (biopsy) In situ SCC 5 Cervix (biopsy) Condyloma 6 Cervix (biopsy) Condyloma 7 Cervix (biopsy) Condyloma 8 Cervix (biopsy) CIN1 + HPV 9 Cervix (biopsy) CIN1 + HPV 10 Cervix (biopsy) CIN1 + HPV 11 Cervix (biopsy) CIN2 + HPV 12 Cervix (cone) CIN3 + HPV 13 Vulva (biopsy) Condyloma 14 Skin Benign vascular neoplasia 15 Skin Granulation tissue 16 Skin Kaposi sarcoma 17 Skin Tyloma (callus) 18 Skin/soft tissues Elastofibroma 19 Skin Benign vascular neoplasia 20 Skin/soft tissues Lipoblastoma 21 Skin Suggestive of SCC (fragments) 22 Skin/soft tissues Low-grade sarcoma (leiomyosarcoma?
The differential diagnosis of a mammary hibernoma includes nonneoplastic inflammatory or reactive processes such as fat necrosis and xanthogranulomatous mastitis, other soft tissue tumors with lipomatous differentiation such as lipoblastomas, and some benign and malignant breast neoplasms such as granular cell tumor and histiocytoid carcinomas.
3] According to Fugemann, the benign lipomatous tumors of this region can be further subclassified as solitary or multiple classic lipomas; infiltrating or intramuscular lipomas; hibernomas; lipoblastomas (socalled fetal lipomas); and diffuse lipomas in children.