lipidation

lipidation

See Protein lipidation.
References in periodicals archive ?
During autophagy, the cytoplasmic form LC3-I (18 kD) is processed and recruited to the autophagosomes, where LC3-II (16 kD) is generated by site-specific proteolysis and lipidation near the C-terminus.
Posttranslational modifications like glycosylation, acetylation, and lipidation occur frequently and further increase the complexity of the proteome (26).
He will highlight his work on the development and analysis of cell-free reactions that replicate the lipidation of the major peripheral autophagosomal protein (LC-3), which plays a primary role in autophagy - a cellular mechanism responsible for the degradation of unnecessary and dysfunctional cellular components.
For instance, genes within region B were thought to encode lipidation enzymes and, thus, have been known as lipA and lipB.
Our team of experts designs the most efficient processes for peptidic active pharmaceutical ingredients using innovative technologies such as PEGylation, lipidation, glycosylation, ligation, cyclization (multiple disulfide or lactam bridges).
PTMs such as lipidation, citrullination, and glycosylation play a vital role in antigen recognition, as they are known to alter its immunogenicity and function.
The implication of this is that lipidation of apolipoprotein A-I by the ABCA1 pathway is necessary for the generation of HDL particles and the clearing of sterol from macrophages.
lipidation and cationization) can be used to improve passive delivery across the blood-brain barrier but is rarely used in isolation.
During autophagy, LC3-1 is converted to LC3-ll through lipidation by a ubiquitin-like system involving Atg7 and Atg3 that allows for LC3 to become associated with autophagic vesicles (Wu et al.
Genetic deficiency of the ABCA1 transporter (Tangier disease) is associated with decreased cholesterol efflux and poor lipidation of pre-[beta] HDL, resulting in accelerated LpAI catabolism and increased CVD (124).
Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1).
This collaboration will focus on exploiting Eukarion's antibody lipidation and chemical modification technologies which could enable KSB's super high affinity sheep monoclonal antibodies (SMA's) to be exploited against novel disease targets.