In contrast, the AF patients on lipid-lowering therapy demonstrated significant improvement over baseline in speed of information processing, memory, and executive function as assessed by switching tests.
Although lipid-lowering therapies, including statins, may lower Lp-PLA2 levels, pharmacologic interventions are now being studied to find ways of best inhibiting the Lp-PLA2 enzyme and potentially providing incremental benefit to intensive lipid-lowering therapy.
In addition, only half of the women who met the criteria of the National Cholesterol Program II guidelines for lipid-lowering therapy were taking statins or other lipid-lowering treatments at enrollment (Ann.
The sub analysis showed a 47 per cent reduction in LDL-C levels among stable coronary artery disease (CAD) patients who remained event-free following aggressive lipid-lowering therapy with LIPITOR(R) (atorvastatin calcium).
Individuals are then stratified into low risk (< 10% risk over 10 years), intermediate risk (10% to 20% risk over 10 years), or high -risk (>20% risk over 10 years) based on their score (1), and this risk score then guides a clinician's decision to institute antiplatelet or lipid-lowering therapy or advise intensive lifestyle modification.
Although there is room for improvement, particularly in very high-risk patients, these results indicate that lipid-lowering therapy is being applied much more successfully than it was a decade ago," said David D.