I recorded whether these coordinates resulted in a "hit" on the opposing team's lipid rafts on blank grids on the overhead projector.
Also, if high school instructors are unfamiliar with the concept of lipid rafts, the activity can be renamed "You Ruptured My Plasma Membrane," with a certain number of hits on coordinates corresponding to target "weak spots" resulting in a win.
Conclusion: Lipid raft mediated Lyn kinase activation seems to be a common mechanism in both epithelial and macrophage cell types but the outcome is different.
Background and Significance: Lipid rafts are cholesterol rich membrane microdomains that bring innate immune receptors like Toll like receptor (TLR) together with signaling molecules like Src family tyrosine kinases to transmit the extracellular events into the cytoplasmic cascade of signaling proteins activation.
Lipid rafts, the sarcoplasmic reticulum and uterine calcium signalling: An integrated approach.
Molecular targets of (-)-epigallocatechin-3-gallate (EGCG): specificity and interaction with membrane
lipid rafts.
Clustering of death receptors in
lipid rafts initiates neutrophil spontaneous apoptosis.
As was recently suggested, these lipid rafts play a role in cellular processes such as early differentiation and apoptosis in human keratinocytes.
also described a correlation between cellular impedance and cholesterol-dependent lateral mobility in lipid rafts.
This collection brings together current hypotheses about the structure and functions of
lipid rafts and caveolae, which are free cholesterol/sphingolipid rich microdomains of the cell surface and assembly sites for many transmembrane signaling complexes.
Other topics of the 20 reviews include
lipid rafts, Rydberg state wavepackets, the quantum mechanics of dissipative systems, semiclassical initial value treatments of atoms and molecules, and heat capacity in proteins.
Topics of the 21 papers include the role of microtubules in transport, kinases- regulating Golgi apparatus structure and functions, N-glycans as apical targeting signals, aspects of dominant distal renal tubular acidosis, regulation of clathrin-coated vesicles and imaging of clathrin-based endocytosism, membrane traffic to and from lysosomes,
lipid rafts in protein interaction and signaling, the role of brain cholesterol in Alzheimer's Disease, endocytosis and retrograde axonal traffic in motor neurons, the biophysics and sociology of ceramides, reversible electrostatic interactions and BAR domains and membrane curvature.
