lipid hypothesis


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lipid hypothesis

Cardiology A widely accepted postulate that hyperlipidemia–eg, cholesterol, and to a lesser degree, other lipids in the circulation is responsible for CAD, the major cause of death in the US, levels which, when altered by dietary or pharmacologic manipulation, ↓ risk of ASHD-related morbidity. Cf Lipid theory.
References in periodicals archive ?
Keys nevertheless persisted in promoting the lipid hypothesis and, as a member of the American Heart Association's nutrition advisory committee, got his theory incorporated into the organization's dietary recommendations, where it has remained ever since.
Rather than questioning the lipid hypothesis, we should be treating those in need earlier and more aggressively.
The lipid hypothesis that dominated American diets for 30 years may now turn out to be total hogwash.
Pollan traces the beginnings of our present epidemic of obesity, metabolic syndrome, and diabetes to the late 1970s, when America bought into the lipid hypothesis, the theory that dietary fat is responsible for chronic disease.
In the past 50 years, a plethora of studies have led most medical scientists and clinicians to accept the lipid hypothesis as truth.
4) In addition, two recent clinical trials have generated results that defy the current dogma of the lipid hypothesis, much to the disappointment of (and cost to) the pharmaceutical sponsors.
With regard to the possible causes of heart disease, the lipid hypothesis can't be reconciled with the carbohydrate hypothesis, and the theory that a deficiency of omega-3 fatty acids contributes to heart disease is at odds with the thesis that refined carbohydrates are the key.
The lipid hypothesis, the label for the diet-heart connection that attributes heart disease to consumption of animal fats, has a long history.
The studies of Keys and his followers became widely popular, and the nutrition and medical communities enthusiastically embraced the diet-heart connection of the lipid hypothesis.
Indeed, it is now a virtual Herculean task to challenge the lipid hypothesis of atherosclerosis/coronary heart disease, and the conclusion that lowering one's cholesterol favors life extension.
Built into the whole cloth of the lipid hypothesis is the postulate that the traditional foods of our ancestors--the butter, cream, eggs, liver, meat and fish eggs that Dr.
But exposure to the research underlying these ideas has caused me to question my acceptance of the lipid hypothesis.