lipase A


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Related to lipase A: amylase, Pancreatic lipase

lipase A

A protein encoded by LIPA  on chromosome 10q23.2 that catalyses the hydrolysis of cholesteryl esters and triglycerides within lysosomes.
References in periodicals archive ?
This shows that the sensitivity of dual testing above the threshold level is 93%, which is only marginally better than the 91% achieved by lipase as a single test.
The data showed that dual testing of lipase and amylase produced a sensitivity of 93% for AP at three times the ULN, which is an improvement of only 2% over lipase as a single test, a marginal gain achieved at double the cost.
The application of lipase as biocatalyst in transesterification of plant oils for biodiesel production offers an environmentally impact more attractive option compared to the conventional process.
Measurements of the activity of both lipase (triacylglycerolacylhydrolase, EC 3.1.1.3) and a-amylase (EC 3.2.1.1) in serum are commonly used as aids in the diagnosis and follow-up of acute and recurrent pancreatitis (1); 19% of pancreatitic patients present with normal serum amylase (2), thus leaving lipase as the main hematochemical marker of this disease in a substantial number of patients.
(5) reported on a non-Hodgkin's lymphoma patient with major lipase activity (up to seven times the upper reference value), with no parallel increase in amylase; in this case, the authors demonstrated a specific immunoglobulin G with high affinity for lipase as the cause of increased serum lipase activity.