Korean biotechnology company IntoCell Inc said on Thursday that it has published its patent application in Korea titled "Compounds Comprising Cleavable Linker
and Uses Thereof" (Application No.
has received honoraria and research support from several pharmacuetical companies.
TMAC - tumour microenvironment activated drug conjugates - is a new form of cancer immunotheraphy combining affimers with chemotherapies in a single drug using a linker
designed to only release the chemotherapy in the tumour microenvironment, Avacta explained.
Despite his overstatement of the threat, Linker
is clearly right on the main point.
Sulfosuccinimidyl-4-(A-maleimidomethyl) cyclohexane-1-carboxylate (Sulfo-SMCC) (Sigma-Aldrich, Wisconsin, USA) is a water-soluble heterobifunctional linker
. It contains an amine-reactive A-hydroxysuccinimide (NHS ester) and a sulfhydryl-reactive maleimide group.
"If this man did not have a diplomatic passport, he would have been arrested," Linker
While the book purports to be a tell-all insider's tale (Linker
served as the editor of First Things from May 2001 until February 2005), the text doesn't begin to support the dust jacket's lurid anticipations.
, on the other hand, argues in The Theocons that it's the religious right, and the First Things coterie in particular, that's doing the encroaching.
According to his former protege, Damon Linker
, that's a serious problem.
Born November 5, 1929, Frank was the loving father of Cheryl (Tim) Kreitz, Christine (John) Negoda, Cathy (Mark) Linker
, Caryn (Fred) Rivera, David (Patty) Roty, cherished grandfather of Jessica Kreitz, Matthew (Samantha) Kreitz, Jason (Jessica) Kreitz, Christopher (Rebecca) Linker
, Megan Linker
, John Negoda, Stephanie Negoda, JD Roty, and proud great grandfather of Caden and Grace.
I am personally acquainted not only with its author, Damon Linker
, but with Richard John Neuhaus and the rest of the so-called "theocons," and I have cause to feel good will towards all parties involved.