lines of Blaschko

lines of Blaschko

(blahs'kō),
a pattern of distribution of skin lesions or pigmentary anomalies; linear on the extremities, S-shaped curves on the abdomen, and V-shaped on the back; thought to result from genetic mosaicism (q.v.) and the interplay of transverse clonal proliferation and longitudinal growth and flexion of the embryo.

lines of Blaschko

Dermatology Alterating stripes of affected and unaffected skin, which are seen in certain skin diseases. Cf Dermatomes.

lines of Blasch·ko

(līnz blas'kō)
A pattern of distribution of skin lesions or pigmentary anomalies; linear on the extremities, S-shaped curves on the abdomen, and V-shaped on the back, thought to result from genetic mosaicism and the interplay of transverse clonal proliferation and longitudinal growth and flexion of the embryo.
References in periodicals archive ?
Majority of the linear lesions follow the lines of Blaschko.
Cutaneous manifestations of IP follow the lines of Blaschko and occur in a chronological sequence of 4 stages, which may temporarily overlap.
Doctors use the lines of Blaschko when diagnosing patients and when carrying out surgery, Dr Shergill added.
It is believed that lines of Blaschko indicate somatic mosaicism reflecting the distribution of clones of abnormal keratinocytes during development.
NS can be found anywhere on the body, but the most common location is on the chest and upper limbs, and often the arrangement of NS follows the lines of Blaschko (3).
Stage III is marked by hyperpigmentation in streaks along the lines of Blaschko in a so-called "marble-cake pattern," she said.
ROME -- Children with pigmentary anomalies along the lines of Blaschko should be watched for signs of central nervous system problems at least until the age of 2 years, Dr.
The term hypomelanosis of Ito is applied to individuals with skin hypopigmentation along the lines of Blaschko.
On cutaneous examination, multiple, linear, hyperkeratotic, verrucous, dry, hyperpigmented papules and plaques were seen over the angle of mandible, ears, neck, anterior and posterior trunk and all extremities including the dorsal surfacesalong the lines of Blaschko (Figure 1 and 2).
Verrucous epidermal nevus follows the lines of Blaschko suggesting that they represent postzygotic mutations.