linear IgA bullous dermatosis


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linear IgA bullous dermatosis

A blistering disease of the skin and mucous membranes characterized by the presence of IgA antibodies in the mucous membranes, serum, and skin. It typically arises after exposure to specific medications, such as amiodarone, captopril, phenytoin, or vancomycin.
See also: dermatosis
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Again complicating the picture is the heterogeneity of serologic findings, that is, circulating IgA antibodies against basement membrane zone antigen are nonspecific to linear IgA bullous dermatosis. Likewise IgG antibodies targeted to BMZ antigen are commonly found in this disease.
The usual treatment for drug-induced linear IgA bullous dermatosis is withdrawal of the suspected agent.
There are no reported cases of linear IgA bullous dermatosis associated with vancomycin contained spacer placement.
In conclusion, linear IgA bullous dermatosis secondary to vancomycin is an uncommon skin disease that may resemble other blistering diseases.
Jablonska, "Linear IgA bullous dermatosis: an immunologically defined disease," International Journal of Dermatology, vol.
Dover, "Vancomycin-induced linear IgA bullous dermatosis," Archives of Dermatology, vol.
Goncalo, "Vancomycin-induced linear IgA bullous dermatosis: associations," Dermatology Online Journal, vol.
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