lineage-restricted

lineage-restricted

In cell biology, functionally and structurally limited to behave in a differentiated manner, e.g. like a fibroblast rather than a neuron, a myocyte, or a blood cell.
References in periodicals archive ?
Postnatal mammary gland development is mediated by lineage-restricted stem cells.
* Development and manipulation of lineage-restricted progenitors is less elaborate.
Citation: "Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors"; Sergei Doulatov et al.; Cell Stem Cell, Volume 13, Issue 4, 459-470, 3 October 2013, DOI: 10.1016/j.stem.2013.09.002
In a study conducted at the Universite libre de Bruxelles, researchers identified a novel lineage-restricted stem cell in the mammary gland.
Citation: Yuval Rinkevich et al.; "In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration": Cell Reports, 2014; 7 (4): 1270 DOI: 10.1016/j.celrep.2014.04.018