Lineage-restricted | definition of lineage-restricted by Medical dictionary
In cell biology, functionally and structurally limited to behave in a differentiated manner, e.g. like a fibroblast rather than a neuron, a myocyte, or a blood cell.
References in periodicals archive
The CD79BxDR SCORPION can bind to two different targets: CD79B, a lineage-restricted
component of the B-cell antigen receptor, and HLA-DR, an HLA Class II molecule.
Based around its proprietary c-mycER(TAM) cell immortalisation technology, ReNeuron has now developed a fully controllable system for generating somatic, or lineage-restricted
, human stem cell lines.