lincosamides


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lincosamides

A group of antibiotics reserved for serious infections with anaerobic and other organisms. They may have serious side effects. An example is clindamycin (Dalactin, Dalactin C, Dalactin D and Zindaclin). Clindamycin as a cream can be used locally to treat ACNE.

lincosamides

bacteriostatic antibiotics that inhibit protein synthesis; includes lincomycin and clindamycin.
References in periodicals archive ?
The erm gene usually confers co-resistance to macrolides, lincosamides, and streptogramins.
A separate in vitro study sponsored by Melinta against contemporary (2017) bacterial strains from acne patients that include isolates resistant to commonly used topical antibiotic treatment showed that 38 percent of samples isolated from skin swabs were multi-drug resistant to macrolides, such as erythromycin, lincosamides, such as clindamycin, and tetracyclines.
But 100% resistance to fluoroquinolones, aminoglycosides and macrolides was noted, while lincosamides showed 97.
95) See NRDC Petition, supra note 80, at 3-4 (listing macrolides, lincosamides, penicillins, streptogramins, tetracyclines, aminoglycosides, and sulfonamides).
aureus isolate(s) from each positive nasal swab were tested for susceptibility to the following 12 classes of antibiotics: aminoglycosides, beta-lactams, cephalosporins, fluoroquinolones, lincosamides, macrolides, oxazolidinones, rifamycin, streptogramins, sulfonamide, nitrofuran, and tetracyclines (see Table S1).
Because they reduce the release of acetylcholine, the effect of the toxin is increased by aminoglicosides, cyclosporine, D-penicillamine, quinidine, succinylcholine, magnesium sulfate and lincosamides, whereas aminoquinolones reduce its effect by blocking its cellular uptake.
The Cfr rRNA methyltransferase confers resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A antibiotics.
Phenotype Resistance to Methicillin, Macrolides and Lincosamides in Staphylococcus Aureus, Isolated in a Hospital in Valledupar, Colombia
The major intramammary antimicrobial treatments that have been used with different success rates to control bovine mastitis include beta-lactams such as natural G penicillins (sodium, potassium, procaine and benzathine), synthetic ones such as ampicillin, amoxicillin and anti-staphylococcus drugs (cloxacillin, oxacillin, nafcillin, meticillin); cephalosporins (Cefapirin, cefalonium, cephalothin, cefoperazone, ceftiofur, cefquinome); aminoglycosides such as dihydrostreptomycin, gentamicin and neomycin; aminocoumarins (novobiocin); fluoroquinolones (norfloxacin); tetracyclines (oxytetracycline); macrolides (erythromycin); lincosamides such as lincomycin and pirlimycin; chloramphenicol, among others.
This gene mediates resistance to not only linezolid but also to phenicols, lincosamides, pleuromutilins, and streptogramin A and macrolides3.