lincosamide

lincosamide

(lin-kōs'a-mīd),
One of a class of antibiotics that work by inhibition of protein synthesis.
References in periodicals archive ?
A low prevalence of inducible macrolide, lincosamide, and streptogramin b resistance phenotype among methicillin-susceptible Staphylococcus aureus isolated from malaysian patients and healthy individuals.
(%) Penicillin ([dagger]) 5 (6.8) 393 (6.0) 0.99 1st-generation 2 (2.7) 445 (6.8) 0.24 cephalosporin 2nd-generation 2 (2.7) 184 (2.8) 0.99 cephalosporin 3rd-generation 26 (35.1) 1,089 (16.7) <0.01 cephalosporin 4th-generation 0 1 0.99 cephalosporin Aminoglycoside 13 (17.6) 118 (1.8) <0.01 Glycopeptide 40 (54.1) 481 (7.4) <0.01 Linezolid 6(8.1) 40 (0.6) <0.01 Carbapenem 42 (56.8) 416 (6.4) <0.01 Tetracycline 12 (16.2) 58 (0.9) <0.01 Trimethoprim- 17 (23.0) 245 (3.8) <0.01 sulfamethoxazole Lincosamide 7 (9.5) 40 (0.6) <0.01 Macrolide 1 (1.4) 286 (4.4) 0.32 Fluoroquinolone 43 (58.1) 871 (13.4) <0.01 Other 5 (6.8) 100 (1.5) <0.01 After matching Case- Control- Variable patients, n patients, = 52 n = 156 p value Ward, no.
Clindamycin, a lincosamide antibiotic has good spectrum of activity against most of the Gram-positive aerobic and anaerobic organisms and acts by inhibiting bacterial protein synthesis (4,18).
Results for antimicrobial resistance in major bacterial isolates revealed; In Pseudomonas resistance to Cephalosporins, polymxins, amino-glycosides, quinolones, penicillin and tetracycline was 66.7%, 55.6%, 55.6%, 66.7%, 66.7% and 88.9% respectively, while 100% strains were resistant to glycyclines, linezolid, vancomycin, macrolides and lincosamide.
According to the results of macrolide phenotypes, the study showed that 17 strains (21.25%) have had constitutive Macrolide, Lincosamide, and Streptogramin B (cMLSB) phenotype and eight strains (10%) have had M phenotype.
Staphylococcus 390 Vancomycin, Mupirocin, Neomycin, Tetracycline, Chloramphenicol, Streptomycin, Spectinomycin, Macrolide, Lincosamide, Streptogramin A and B, Fosfomycin, Pleuromutilin, Trimethoprim, Apramycin, Phenicols, Oxazolidinones, Erythromycin, Gentamicin, Apramycin, Methicillin, Bleomycin, Antiseptic, Isoleucine, Pleuromutilins, Kanamycin, Trimethoprim, Minocycline and Penicillins.
Tober, Specific Inhibition of 50S Ribosomal Subunit Formation in Staphylococcus aureus Cells by 16-Membered Macrolide, Lincosamide, and Streptogramin B Antibiotics.
Molecular basis of macrolide, triamilide, and lincosamide resistance in Pasteurella multocida from bovine respiratory disease.
Part two covers structure-activity details of some particular drug successes, including epothilones, taxol, camptothecin, morphine, lincosamide, platensimycin, phlorizin, aeruginosins, and their analogs.
The product is a lincosamide antibiotic and benzoyl peroxide indicated for the topical treatment of acne vulgaris.
Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics.
Cloacal Lactobacillus isolates from broilers show high prevalence of resistance towards macrolide and lincosamide antibiotics.