limit of detection


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limit of detection

Abbreviation: LOD
The smallest amount of an analyte that can be detected by an analytical system.
See also: limit
References in periodicals archive ?
No signals corresponding to heroin were observed in any sample, and a signal above the limit of detection (0.007 compared with 0.003) was observed for 6-monoacetylmorphine in only 1 of the 99 fingerprints tested.
Limit of detection (LOD) was calculated to be 0.478 mM which was better than that of the previous report of 0.58 mM (Hamzah et al., 2013).
In calculation of geometric means, values lower than the limit of detection of AFB1 and AFM1 were replaced by half the value of the limit of detection for the respective kits to avoid biasing the results.
(2011) used LIBS to find the calibration curve and limit of detection of Eu in glass samples that were certified standard reference materials.
The limit of detection (LOD) and limit of quantitation (LOQ) of vasicine, glycyrrhizin, eugenol, and cineole show adequate sensitivity of method.
The limit of detection is calculated to be around 10 nanomolar through this method.
The gold standard for monitoring of antiretroviral treatment is regular monitoring of plasma viral load, both to determine that undetectable viral load has been achieved after starting treatment and to ensure that viral load does not rebound above 50 or 400 copies/ml, the limit of detection of the viral load test.
Each monograph has information on its names, category, molecular formula and weight, appearance, solubilities, and other chemistry, and methods, including the analytical system components, major operating parameters, standard solution and sample preparations, correlation coefficient and linearity, coefficient of variation of the assay, limit of detection and quantification, and interference.
Among patients who received the highest doses of treatment (1,000 mg RG7128 twice daily plus 900 mg of danoprevir twice daily), "five of eight treatment-naive patients and two of eight [previous] null responders [to standard HCV therapy] had HCV RNA concentrations below the limit of detection (less than 15 IU/mL)." Additionally, "seven of eight treatment-naive patients and four of eight null responders had HCV RNA concentrations below the limit of quantification (43 IU/mL)," the authors wrote.
Its limit of detection without pre-enrichment steps could amount to 10 CFU per mL within four hours.
Literature about methylene blue presents contradictory reports about its limit of detection of DNA, with reports typically suggesting at least one tenth the sensitivity of ethidium bromide (see, for example, Madden 2006 and Brown 2000).
When used in combination with the Thermo Scientific FOCUS GC, the ITQ 700 GC/MS achieves an unprecedented average relative standard deviation of 9.7% of four replicate analyses at 50 ng/g and a calculated average limit of detection of 2.7 ng/g in iceberg lettuce, based on eight replicate analyses of 5 ng/g, well below all published Minimum Reporting Limits (MRL).