SGCB

(redirected from limb girdle muscular dystrophy 2E (non-linked families) LGMD2E)

SGCB

A gene on chromosome 4q12 that encodes beta-sarcoglycan, a transmembrane component of the dystrophin-glycoprotein complex, which help stabilise muscle fibre membranes and link the muscle cytoskeleton to the extracellular.

Molecular pathology
SGCB  is mutated in in patients with limb-muscle muscular dystrophy type 2E.
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