light chain nephropathy
light chain diseaseA nephropathy which presents with nephrotic range proteinuria and rapidly progressive renal failure due to deposition of electron-dense material within tubular and glomerular basement membranes.
Nephrotic syndrome, heart failure, arrhythmias, liver disease, anorexia, nausea, weight loss, anaemia, increased creatinine, and neurologic disease; similar clinical findings occur in heavy chain deposition.
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light chain nephropathyNephrology A condition characterized by deposition of monoclonal light chains and electron-dense material in tubular and glomerular basement membranes Clinical Anorexia, nausea, weight loss, anemia, ↑ creatinine, ESRD; LCN may accompany myeloma
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.