ligand


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ligand

 [li´gand, lig´and]
an organic molecule that donates the necessary electrons to form coordinate covalent bonds with metallic ions. Also, an ion or molecule that reacts to form a complex with another molecule.

lig·and

(lig'and, lī'gand),
1. Any individual atom, group, or molecule attached to a central metal ion by multiple coordinate bonds, for example, the porphyrin portion of heme, the corrin nucleus of the B12 vitamins.
2. An organic molecule attached to a tracer element, for example, a radioisotope.
3. A molecule that binds to a macromolecule, for example, a ligand binding to a receptor.
4. The analyte in competitive binding assays, such as radioimmunoassay.
5. An atom or group covalently attached to a specified carbon atom in an organic molecule.
[L. ligo, to bind]

ligand

(lī′gənd, lĭg′ənd)
n.
An ion, molecule, or molecular group that binds to another chemical entity to form a larger complex.

li·gand

(lī'gand)
1. An organic molecule attached to a central metal ion by multiple coordinate bonds.
2. An organic molecule attached to a tracer element, e.g., a radioisotope.
3. A molecule that binds to a macromolecule, e.g., a ligand binding to a receptor.
4. The analyte in competitive binding assays, such as radioimmunoassay.
[L. ligo, to bind]

ligand

A MOLECULE or ION that binds to a central chemical entity by non-covalent bonds. A general term for any molecule that is recognized by a surface receptor.

ligand

a molecule able to bind to a specific ANTIBODY and used to distinguish closely similar types of antibody.

li·gand

(lī'gand)
1. Any individual atom, group, or molecule attached to a central metal ion by multiple coordinate bonds.
2. An organic molecule attached to a tracer element.
3. A molecule that binds to a macromolecule.
[L. ligo, to bind]
References in periodicals archive ?
Ligand (L2)###C36H50N204###574###Yellowish Crystalline###275
Table-3: 1H NMR Spectroscopic data, I' (ppm), of Ligand L1 and its complexes.
To read Lemelson's prior research reports and commentary on Ligand click here
"Ligand is a company designed for the 'lazy investor' whose stock price has 80-percent downside from its current levels," Left said.
The ligand and its metal complexes were tested for their anti-bacterial activity against two bacterial species i.e.
A sample of the resulting plots is shown in Figure 3 and it is evident that 1:1 (metal ion to ligand) complexes are formed in solution.
For this purpose, a mixture of 0.3 g (0.00045 mol) P(DEAMSt13%-co-St)L" ligand dissolved in 40 mL ethanol was stirred for 2 h at 65[degrees]C and the pH of the solution was calibrated by adding dilute 0.1 M NaOH solutions in water.
We were able to obtain 1,031 unique hub structures and 1.741 unique cycle structures from 213,919 ligands. We then count the frequencies of those hubs and cycles for each ligand, so each ligand has a vector with a length of 2,776 (=1,031 + 1.741 + 4).
The study shows that systematic structural variations made to the polypyridyl ligand can be described in terms of the effect on the vibrational coherence across the complex.
All of these experimental studies were based on the determination of the interaction of a labeled reporter ligand with the receptor by filtrating samples through GF/B filters.
The TMPyP4 (5,10,15,20-tetrakis-(1-methyl-4-pyridyl)-21H, 23H-porphyrin) is one ligand shown to be capable of binding to the G4-structures.
Moreover, after the initial submission of the present manuscript, Gutjahr and coworkers recently published that coapplication of a similar dual TLR2/7 ligand PamadiFectin (CL307) and HIV-1 antigen p24-coated nanoparticles can efficiently boost HIV-specific antibody responses while also inducing a balanced Th1/Th2 profile in mice [16].

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