Although there are several locations for median nerve entrapment like ligament of struthers
, anomalous arteries, and muscles, but the pronator syndrome remains the most common reason for compression neuropathies of median nerve in the forearm.
The ligament of Struthers was first described as a fibrous band extending from the supracondylar (supracondyloid) process or spur on the anteromedial aspect of the humerus downwards to the medial epicondyle  which occurs in <2% of humans.
Several cases of median nerve entrapment have been attributed to the presence of ligament of Struthers. The ligament of Struthers complex is well known to cause neurovascular compression syndromes.