In the studied group, prick tests with a set of the most common environmental allergens (Allergopharma-Nexter, Poland) and 2%
lidocaine without vasoconstrictors, were performed on the inner part of the forearm.
Thus, the purpose of this study was to compare the anaesthetic success rate of buccal infiltration combined with intraligamentary injections of 4% articaine and 2%
lidocaine in mandibular molars with irreversible pulpitis.
Also under development is a topical system with a three-fold higher concentration of
lidocaine, which takes advantage of ZTlido's thinner and more efficient delivery system to potentially address other types of pain.
They used the active ingredient
lidocaine in both groups and reported that patients who underwent PPNB had significantly less pain.
Four patients were excluded due to faint following local anesthetic injection (2 patients from
lidocaine regimen and 2 from prilocaine regimen) and were excluded consequently according to study protocol and official clearances.
With IV
lidocaine, the number of good outcomes in acute treatment is increasing (2,3).
(28) Case series using combination
lidocaine plus methylprednisolone (29) or betamethasone (30,31) showed promising results.
The operating room research pharmacy prepared for the first group (
lidocaine bolus or Group-LB) a syringe containing 2 ml of 2%
lidocaine (40 mg) and a syringe containing 1 ml of normal saline.
Procedure followed in the Study Group (Group 1) of all 50 patients was - 2 mL (2%
lidocaine HCl with 1: 100,000 epinephrine) administered in the mucobuccal fold under aseptic technique.
Lidocaine hydrochloride, ketorolac, and hexafluoroisopropanol were also purchased from Sigma-Aldrich.
Patients who refused; patients with Reynauld's disease, sickle-cell disease, crush injuries, and swelling or skin infection at the site of injection; and patients with a history of allergy to nitroglycerin or
lidocaine and surgeries >60 minutes or <30 minutes were excluded from the study.
The Study: In this study, 352 infants were divided into four treatment groups: a video not related to infant soothing techniques (the placebo control); parental video education on soothing infants; video plus orally administered sucrose; video plus sucrose plus topical
lidocaine applied at the injection site.
