For example, in the above query, the ontology returns the following result: "ChloasmaFaciei 46, Melasma 46, Ephelides 46, Freckles 46, Lichenoid Keratosis
46, Mask Of Pregnancy 46, Benign Lichenoid Keratosis
46, Lupus Panniculitis 36."
Differential Diagnoses of Seborrheic Keratosis (1,3) Permanent or Malignant Lesions Benign Lesions * Actinic keratosis * Acrochordon (skin tags) * Bowen disease (SCC in situ) * Acrokeratosis verruciformis * Invasive SCC / SCC in situ * Benign lichenoid keratosis
* Lentigo maligna * Condyloma acuminatum * Malignant melanoma * Eocrine poroma/hidroacanthoma simplex * Pigmented basal cells * Melanooytic nevus * Verruca vulgaris (warts) * Solar lentigo (liver spots) * Tumor of the infundibulum SCC=squamous cell carcinoma.
There has also been report of lichenoid keratosis
with ranibizumab use .
is a very common diagnosis with lesions most often occurring on the trunk and proximal upper limbs of middle-aged or older patients.
Classical lichen planus 73.3% cases was the most common diagnosis, which was followed by lichen planus pigmentosus 8.3% cases, follicular lichen planus 5% cases, lichen nitidus 3.3% cases, each of lichen planus hypertrophicus, lichen planus atrophicus, lichen planus actinicus, benign lichenoid keratosis
, lichenoid eruption, and lichen striatus as 1.7% cases.
Over 60% of the lesions are beniign,5 however, malignant or premalignant lesiions might be associated in upto 20-40% f case.6 The benign skin conditions asssociated with cutanous horns7,8 include soolar keratosis, angioma, angiokeratoma, cutaneous leishmaniasis, lichenoid keratosis
, epidermal nevi, epidermal acanthomaa, seborrheic keratosis, sebaceous adenoma, trichilemmoma, sebaceous molluscum and verruca vulgaris.
Idiopathic benign lichenoid keratosis
on the pinna of the ear in four dogs.
TABLE Some causes of cutaneous horn Benign--noninfectious Angiokeratoma Angioma Dermatofibroma Epidermal inclusion cyst ("sebaceous cyst") Linear verrucous epidermal nevus Fibroma Lichen simplex chronicus ("neurodermatitis") Lichenoid keratosis
Prurigo nodularis Pyogenic granuloma Sebaceous adenoma Seborrheic keratosis Trichilemma Benign--infectious Condyloma acuminata (genital warts) Molluscum contagiosum Verruca vulgaris (common wart) Premalignant/malignant Actinic keratosis Basal cell carcinoma Bowen's disease Epidermoid carcinoma Kaposi's sarcoma Keratoacanthoma Malignant melanoma Squamous cell carcinoma Sources: Gould and Brodell 1999, (1) Akan et al 2001, (6) Khaitan 1999.
Superficial BCC may mimic a lichenoid keratosis
, Bowen's disease, or other inflammatory conditions such as psoriasis and dermatitis.
Some of the pseudolymphomas that can fool the clinician include lymphomatoid drug eruption, cutaneous leishmaniasis, lymphomatoid lichenoid keratosis
, and reactive lymphoid hyperplasia at the site of vaccination.
The principal differential diagnosis in this category lies between lupus erythematosus and lichenoid keratosis
. Although lichen planus and lupus are usually readily distinguishable from one another, lichenoid keratosis
has intermediate features and can be more difficult to distinguish from lupus, requiring the evaluation of multiple criteria.
Paramount among these are atypical squamoproliferative lesions with lichenoid inflammation, such as benign lichenoid keratosis
, lichenoid actinic keratosis, and squamous cell carcinoma.