levomethadyl

levomethadyl

 [le″vo-meth´ah-dil]
an opioid analgesic used as an adjunct in the treatment of opioid addiction; administered orally as the acetate hydrochloride salt.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
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Itraconazole is a potent inhibitor of CYP3A4 and may result in serious cardiovascular events if used simultaneously with eisapride, pimozine, quinidine, or levomethadyl. It must be used with caution when treating onychomycosis in patients with congestive heart failure or other ventricular dysfunction.
Through the cytochrome P-450 system, many antiretroviral agents interact with opioids, including methadone (see box), levomethadyl acetate (LAAM), and buprenorphine.
Through the cytochrome P-450 system, many antiretroviral agents interact with opioids, including methadone, levomethadyl acetate (LAAM), and buprenorphine.
(8) Nine noncardiac medications were affected, including terfenadine, astemizole, grepafloxicin, terodiline, droperidol, lidoflazine, sertindole, levomethadyl, and cisapride.
Levomethadyl acetate is a longer-acting version of methadone that's been on the market for several years.
Another labeling change makes Orlaam (levomethadyl acetate hydrochloride) a second-line therapy and recommends reserving its use for those patients who fail to show an acceptable response to other treatments.
In a 17-week study, 220 subjects were randomized to receive levomethadyl acetate (75-115 mg/day), buprenorphine (16-32 mg/day in an alcohol solution), methadone 60-100 mg/day or methadone 20 mg/day.