Beta Blockers acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, celiprolol, esmolol, labetalol, levobunolol
, metipranolol, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol
Although prescribers could turn to alternative preservative-free beta-blockers such as betaxolol (Betoptic), levobunolol
(Betagan) or, following its launch in October 2011, the low-strength timolol preservative-free gel Tiopex for patients on Timoptol preservative-free, there was no alternative for patients on the other products, necessitating a review of treatment.
The antiglaucoma beta blockers include betaxolol (Betoptic), carteolol (Ocupress), levobetaxolol (Betaxon), levobunolol
(Betagan), metipranolol (Optipranolol) and timolol (Betimol, Timoptic, Istalol).
Table 7: Global Osteoporosis Drug Market (2006): Breakdown of Value Sales of Leading Drug Brands - Fosamax, Evista, Boniva, Forteo, Actonel and Miacalcin (In US$ Million) (includes corresponding Graph/Chart) II-51 Osteoporosis Therapeutics: A Peek into the Major Brands II-52 Arthritis II-52 Cataract II-53 Glaucoma II-53 Anti- Glaucoma Ophthalmic Drugs II-53 Beta-Adrenergic Blockers or "Beta Blockers" II-54 Timolol II-54 Levobunolol
II-54 Carteolol II-54 Metipranolol II-55 Betaxolol II-55 Carbonic Anhydrase Inhibitors II-55 Prostaglandins II-55 Miotics II-55 Other Treatments II-55
Timolol II-68 Levobunolol
II-68 Carteolol II-68 Metipranolol II-69 Betaxolol II-69 Carbonic Anhydrase Inhibitors II-69 Prostaglandins II-69 Miotics II-69 Other Treatments II-69 Age-Related Macular Degeneration (AMD) II-70 Benign Prostatic Hyperplasia II-70 Dementia II-70 Alzheimer disease II-70 Menopause II-70 Age-Related Cardiovascular Diseases II-71 Sexual Dysfunction/Impotence II-71 Supplements for Age-Related Health Conditions II-71 Nutraceuticals II-72 Amino Acids II-72 Bay II-74
He was then given levobunolol
and later brinzolamide eye drops (individually).
(Betagan) Manufactured by Allergan (NYSE:AGN)
Helix previously obtained the Canadian marketing and distribution rights to Levobunolol
under the terms of its agreement with Bausch & Lomb Pharmaceuticals, a world leader in the manufacture of ophthalmic pharmaceuticals.
Food and Drug Administration (FDA), and levobunolol
hydrochloride ophthalmic solution, for which FDA approval is currently pending.
In March, the company announced positive Phase III results using its BetaSite(TM) formulation of levobunolol
to treat glaucoma.
3% Ophthalmic Solution) and Levobunolol
Hydrochloride Ophthalmic Solution, which are two ophthalmic beta-blocker solutions, and Pilostat(R) (Pilocarpine Hydrochloride Ophthalmic Solution).
As announced during the first quarter, our BetaSite(TM) eyedrop formulations of levobunolol
have demonstrated success in a 670 patient Phase III clinical study for the treatment of glaucoma," said Kumar Chandrasekaran, Ph.