levamisole


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Related to levamisole: Levamisole hydrochloride

levamisole

 [le-vam´ĭ-sōl]
an oral imidazole that enhances the immume response and is used as the hydrochloride salt as an adjuvant to fluorouracil in antineoplastic therapy after surgery in patients with Dukes' stage C colon cancer.

le·vam·i·so·le

(lē-vam'ĭ-sōl),
Formerly used as an anthelmintic; increases immune responses and is used adjunctively with fluorouracil to improve response and suppress recurrence.

levamisole

Oncology A broad-spectrum anthelmintic that stimulates immune function, enhancing hypersensitivity; it has been used with 5-FU to ↑ Pt survival in advanced colorectal and other CAs Adverse effects N&V, diarrhea, rash, flu-like Sx. See Unproven methods for cancer management Parasitology An l- form of tetramisole, which is most commonly used anthelmintic for roundworm, hookworm, Strongyloidesinfections.

le·vam·i·sole

(lē-vam'ĭ-sōl)
Drug that increases immune responses; used adjunctively with fluorouracil to improve response and suppress recurrence.

levamisole

An ANTHELMINTIC drug used to remove roundworms. It has also been found to have an unexpected effect in stimulating the immune system by increasing T cell responsiveness and encouraging the activity of polymorphonuclear LEUCOCYTES and MACROPHAGES. It is effective in rheumatoid arthritis. Adverse side effects limit its use. The drug is on the WHO official list.
References in periodicals archive ?
(p<0.001) With treatment of levamisole, and GSE 25 as well as 50 mg/kg the relative organ weights were significantly increased in comparison to that of CP treated rats as shown in Table-1.
Only treatment of Levamisole has been tried with three injections at weekly interval in repeat breeder cases and 60 percent conception rate has been recorded by Kaswain et al.
"It's a little bit like having HIV" said Dr Noah Craft, a dermatologist at the Harbor-UCLA Medical Center, during a 2011 spate of levamisole poisoning cases in the US.
The aim ofthis study is to determine the capability of levamisole to enhance the humoral antibody response and cell-mediated immunity as well as protective capacity of [RB.sub.51] vaccine in mice against challenge with virulent B.
An example is a farmer I found using Levamisole to deworm her sheep, yet the worms she had seen the sheep voiding were tapeworms.
Levamisole hydrochloride salt is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives.
A combination of 0.5mg/kg moxidectin, 9.06mg/kg oxfendazole, 15mg/kg levamisole HCI, and 0.08 mg/kg selenium was administered.
Mice in the positive control group were given 2.5 mg/kg BW/d levamisole hydrochloride (LH) in a similar manner as the sublancin treatment.
The Drug Enforcement Administration was the first organization to report the presence of levamisole (LVM) as a cutting agent in illicit cocaine (Valentino & Fuentecilla, 2005).
Many treatment methods, such as oral or topical phenylalanine administration, benefiting from the antioxidant effects of alpha-lipoic acid preparations, oral administration of vitamin B12, folic acid, other vitamins and trace elements, use of oral levamisole, use of topical prostaglandin analog, topical application of placental extract (melagenina), topical application of 5-FU, and kheillin+ultraviolet A application, are included in experimental treatments (6-10).
Many drugs have been used, including diethylcarbamazine, ivermectin, mebendazole, levamisole, albendazole, and thiabendazole (1).
Levamisole is a pharmaceutical agent typically used as an anthelmintic in livestock, but, since 2007, it has increasingly been found as an adulterant in cocaine.