levamisole


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Related to levamisole: Levamisole hydrochloride

levamisole

 [le-vam´ĭ-sōl]
an oral imidazole that enhances the immume response and is used as the hydrochloride salt as an adjuvant to fluorouracil in antineoplastic therapy after surgery in patients with Dukes' stage C colon cancer.

le·vam·i·so·le

(lē-vam'ĭ-sōl),
Formerly used as an anthelmintic; increases immune responses and is used adjunctively with fluorouracil to improve response and suppress recurrence.

levamisole

/le·vam·i·sole/ (le-vam´ĭ-sōl) an immunomodulator used with fluorouracil in the treatment of colon cancer, administered as the hydrochloride salt.

levamisole

an immunomodulator used as an adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer.

levamisole

Oncology A broad-spectrum anthelmintic that stimulates immune function, enhancing hypersensitivity; it has been used with 5-FU to ↑ Pt survival in advanced colorectal and other CAs Adverse effects N&V, diarrhea, rash, flu-like Sx. See Unproven methods for cancer management Parasitology An l- form of tetramisole, which is most commonly used anthelmintic for roundworm, hookworm, Strongyloidesinfections.

le·vam·i·sole

(lē-vam'ĭ-sōl)
Drug that increases immune responses; used adjunctively with fluorouracil to improve response and suppress recurrence.

levamisole

An ANTHELMINTIC drug used to remove roundworms. It has also been found to have an unexpected effect in stimulating the immune system by increasing T cell responsiveness and encouraging the activity of polymorphonuclear LEUCOCYTES and MACROPHAGES. It is effective in rheumatoid arthritis. Adverse side effects limit its use. The drug is on the WHO official list.

levamisole

a broad-spectrum anthelmintic of proven efficiency against gastrointestinal and lung worms that can be administered orally, by injection and by pour-on in cattle. It has no effect on tapeworms or liver fluke; it has a secondary effect in enhancing depressed immune responsiveness by stimulation of T lymphocytes and phagocytosis.

levamisole poisoning
causes a syndrome of lip licking, head shaking, salivation, tremor, excitement and increased frequency of urination and defecation.
References in periodicals archive ?
Neutrophil dysfunction and repeated infections: influence of levamisole and ascorbic acid.
These results show a signifi-cant rise in resistance levels compared to the previous study undertaken in 2006, when 78% were resistant to Benzimidazole, 34% were resistant to Levamisole and resistance to the other two wormers was considered to be low," said Mrs Davies.
The figures represent a big rise in resistance levels compared to a 2006 study when 78% of farms were resistant to Benzimidazole, and 34% to Levamisole.
Initial uses of Levamisole were to eliminate parasitic worm infections in cattle and humans.
Relevant to this manuscript, levamisole has also been recognized as an adulterant in illicit cocaine since 2003 (3).
The intervention group received 150mg oral levamisole (an antihelminthic drug with immunomodulatory properties) while the control group took a placebo tablet on two consecutive days weekly.
Comparison of the efficacy of dermal formulations of ivermectin and levamisole for the treatment and prevention of Dictyocaulus viviparous infection in cattle.
Effects of praziquantel, miclosamide, levamisole hydrochloride and metrifonate on Monogenea (Gyrodactylus aculeati, Diplozoon paradoxum).
Sun A, Wang P, Chia J-S, Liu B-Y, Chiang C-P: Treatment with levamisole and colchicine can result in a significant reduction of IL-6, IL-8 and TNF-a level in patients with mucocutaneous type of Behcet's disease.
Tim Morris, BHA director of equine science and welfare, told the Racing Post at the weekend that the authority would in future seek more severe penalties following the discovery of tetramisole or levamisole - essentially the same drug - or pemoline, as the BHA had cautioned trainers about its use in stable visits and a notice dated May 27, which also appeared in the National Trainers' Federation's newsletter.
Those symptoms are consistent with use of the medication levamisole, which is used by veterinarians for de-worming farm animals.
Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report.