leukotriene modifiers

leukotriene modifiers

pharmacologic agents used to interrupt the pathways of leukotriene activation.
See also: antileukotriene.
References in periodicals archive ?
Current medications for asthma are effective and facilitate a multi-pronged approach, and include inhaled corticosteroids, long-acting bronchodilators (beta-agonists and anticholinergics), theophylline, leukotriene modifiers, and more recent strategies such as the use of anti-immunoglobulin E (IgE) antibodies (omalizumab) and anti-IL-5 antibodies.
Leukotriene modifiers affect only one biochemical pathway--the lipoxygenase path and resulting leukotriene effects.
USPRwire, Thu Oct 23 2014] Asthma accounts for approximately 250,000 deaths around the world annually, deaths that otherwise could be easily prevented through appropriate treatment The asthma market saw very slow growth over the past decade, as it has become saturated with relatively efficacious standard therapies, such as short-acting beta-agonists (SABAs), inhaled corticosteroids (ICSs), inhaled corticosteroids and long-acting beta-agonists (ICS/LABAs), and leukotriene modifiers, and has also been facing increasing generic competition.
Leukotriene modifiers are a form of anti-inflammatory medication that helps prevent asthma symptoms for up to 24 hours.
Patients were allowed to continue the use of stable doses of sustained-release theophylline, leukotriene modifiers, anti-immunoglobulin E antibody, or oral glucocorticoids, and were given open-label inhalers of salbutamol or albuterol for use as rescue medication.
From these patients, the researchers looked for individuals who were new users of asthma controller medications, including inhaled corticosteroids, long-acting beta-agonists or leukotriene modifiers, or IACs, and who had continuous enrollment in the IMS system for at least six months prior to having the control medication dispensed.
On the other hand, women were significantly more adherent than men were for leukotriene modifiers (0.
If these cognitive symptoms bother you, speak to your health care provider, who may adjust dosage levels or suggest alternative drugs such as leukotriene modifiers (Singulair; Zyflo), mast cell stabilizers (Crolom; Nasalcrom; Tilade), or the antibody omalizumab (Xolair), which prevents the release of inflammatory chemicals that narrow the airways.
The goalposts have changed recently with the addition of long-acting beta 2 agents such as salmeterol and the recent advent of leukotriene modifiers.
He or she may recommend adjusting dosage levels or replacing corticosteroid therapy with alternative drugs such as leukotriene modifiers (Singulair; Zyflo), mast cell stabilizers (Crolom; Nasalcrom; Tilade), or the antibody Omalizumab (Xolair), which prevents the release of inflammatory chemicals that narrow the airways.
Leukotriene modifiers are a new form of anti-inflammatory medication used to treat chronic asthma and may also be used as an alternative therapy for treating mild-to-moderate persistent asthma or as combination therapy in moderate asthma.