leukotoxin

leukotoxin

 [loo´ko-tok″sin]
a toxin that destroys leukocytes.

leu·ko·cy·to·tox·in

(lū'kō-sī'tō-tok'sin),
Any substance that causes degeneration and necrosis of leukocytes, including leukolysin and leukocidin.
Synonym(s): leukotoxin
[leukocyte + G. toxikon, poison]

leu·ko·cy·to·tox·in

(lū'kō-sī'tō-tok'sin)
Any substance that causes degeneration and necrosis of leukocytes, including leukolysin and leukocidin.
Synonym(s): leukotoxin.
[leukocyte + G. toxikon, poison]
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References in periodicals archive ?
Outer membrane-like vesicles secreted by Actinobacillus actinomycetemcomitans are enriched in leukotoxin. Microb Pathog 2002; 32:1-13.
bacteriovorus SSB218315 also encodes genes annotated as RTX toxins, a factor that has different biological functions such as pore-forming leukotoxin, metalloprotease, and lipase activities [33].
find another periodontal germ called Aggregatibacter actinomycetemcomitans (Aa) can induce hypercitrullination in host neutrophils through its leukotoxin A (LtxA).
intermedius) carry several virulence factors i.e coagulase, clumping factors, haemolysin and leukotoxin, pyogenic toxins comprising staphylococcal enterotoxins, toxic shock syndrome toxin 1, and S.
Leucotoxic activities of Staphylococcus aureus strains isolated from cows, ewes, and goats with mastitis: importance of LukM/LukF'-PV Leukotoxin. Clin.
[32] The pathogenicity of the microorganism is also underlined by its well-characterized virulence factors, such as leukotoxin and cytolethal distending toxin, which are suggested to play important roles in altering host inflammatory responses as well as in contributing to periodontal disease progression.
Additional candidates have been highlighted in the literature, including the leukotoxin LukED which targets the human CCR5 receptor (Alonzo, 2013).To ensure the development of efficacious and safe vaccine antigens, the research project proposes the structure-based optimization of two candidate antigens: (i) an antigen engineered from the Csa protein family that we recently discovered and characterized (Schluepen, 2013) and (ii) an engineered detoxified leukotoxin-E antigen.
actinomycetemcomitans Leukotoxin Inhibition of PMN function.
Kato, "Interaction of Actinobacillus actinomycetemcomitans outer membrane vesicles with HL60 cells does not require leukotoxin," Cellular Microbiology, vol.