leukostasis

leukostasis

 
increased blood viscosity and tendency to clotting, seen in leukemia that is accompanied by hyperleukocytosis.

leukostasis

increased blood viscosity and tendency to clotting, seen in leukemia that is accompanied by hyperleukocytosis.

leukostasis

(loo″kō-stā′sĭs) [ leuko- + stasis]
Obstruction of blood vessels by excessive numbers of immature white blood cells, esp. in patients who have leukemia. The excessive concentration of white blood cells increases the viscosity of the blood, causing it to turn into sludge in small vessels, such as those in the brain and the lung.
References in periodicals archive ?
Stimulated WBCs have an increased tendency to adhere to vascular endothelium, and they easily penetrate the intima, causing both capillary leukostasis and increased vascular resistance.
Acute pulmonary edema due to recent NSTEMI, bilateral pneumonia (blood culture later reported as positive for Staphylococcus epidermidis), leukostasis, and differentiation syndrome were considered in the differential diagnoses.
Several factors in lymphoma may contribute to kidney vasculature thrombosis, such as leukostasis, malignancy-associated nephrotic syndrome, and treatments that activate the clotting cascade (Luciano & Brewster, 2014).
8) The presence of hyperleukocytosis is a poor prognostic indicator because most patients incur leukostasis (vascular obstruction/tissue hypoxia), tumor lysis syndrome, and/or disseminated intravascular coagulation (DIC).
Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy.
These processes are known to begin far in advance of any clinical evidence of retinopathy and are associated with increased retinal leukostasis.
However, an inflammatory component was supported by the finding that vascular apoptosis was blocked by the systemic administration of antibody to Fas ligand, preventing leukostasis.
Hematologic emergencies include febrile neutropenia, hyperviscosity syndrome (HVS), hyperleukocytosis and leukostasis and bleeding.
Both pulmonary leukostasis and malignant infiltration of the lung have been described in patients with AML (4).
This naturally occurring compound is a potential therapeutic agent in the treatment of inflammatory diseases and in vivo leukostasis treatments.
Hyperleucocytosis associated with pulmonary and cerebral leukostasis in acute myeloid leukemia-
A pronounced leukostasis in vascular channels and interstitial infiltrates of small, blue cells were present in nearly all tissues examined, with pronounced infiltrate in the endocardial surface (Figure 2) of the heart.