Despite continued debate, leukoreduction
is considered by many to be adequate for TT-CMV mitigation for all patient populations.
8) in the Netherlands in this context identified non-leuco-reduction as being associated with increased incidence of multiorgan dysfunction, infection and length of hospital stay (8) resulting alongside other studies in the immediate initiation of the EU directive for pre-storage leukoreduction
to be required for all banked blood.
for the prevention of adverse reactions from allogeneic blood transfusion.
The association of red cell transfusions with post-operative infections has been shown in randomized clinical trials to be partially mitigated by leukoreduction
Contract notice: Acquisition of integrated systems for harvesting bags and automatic separation of whole blood by centrifugation and simultaneous expression as well as systems for pooled platelets with integrated leukoreduction
filter and use of additive solution, placement of appropriate equipment for this purpose in the service immuno-blood therapy for a period of 36 months.
Leukapheresis rapidly yields leukoreduction
and is the initial treatment of hyperleukocytosis with symptoms.
In addition, incidence of transfusion-related reactions has decreased considerably due to prestorage leukoreduction
Conducting new RCTs on the effects of leukocyte-containing RBCs in countries that implemented universal leukoreduction
of blood products is not possible.
For example, to help streamline blood center operations, the new Auto RBC function automates the in-line leukoreduction
of red blood cells (RBCs), which eliminates the need for lab processing with ready-to-store, leukoreduced RBC products.
The observational study was conducted during the seven years before and after 2000, when the URMC introduced universal leukoreduction
, a process that filters the white cells from blood to be used for transfusions.
Since latent CMV is found in peripheral blood monocytes (7), there are a lot of studies that refer a decrease in the transmission of CMV by leukoreduction
of blood components.
Other preventive strategies (such as leukoreduction
filtration, saline-washed RBCs, frozen deglycerolised RBCs, etc.