leukoerythroblastosis


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leukoerythroblastosis

 [loo″ko-ĕ-rith″ro-blas-to´sis]
anemia due to destruction or crowding out of hematopoietic tissues in the bone marrow by a space-occupying lesion; reduction in normal marrow cells induces release of immature hematopoietic cells, especially nucleated erythrocytes, into the bloodstream. Called also myelopathic or myelophthisic anemia.

leu·ko·e·ryth·ro·blas·to·sis

(lū'kō-ĕ-rith'rō-blas-tō'sis),
Any anemic condition resulting from space-occupying lesions in the bone marrow; the circulating blood contains immature cells of the granulocytic series and nucleated red blood cells, frequently in numbers that are disproportionately large in relation to the degree of anemia.

leukoerythroblastosis

/leu·ko·eryth·ro·blas·to·sis/ (-ĕ-rith″ro-blas-to´sis) anemia associated with space-occupying lesions of the bone marrow that cause bone marrow suppression with a variable number of immature cells of the erythrocytic and granulocytic series in the circulation.

leu·ko·e·ryth·ro·blas·to·sis

(lū'kō-ĕ-rith'rō-blas-tō'sis)
Any anemic condition resulting from space-occupying lesions in the bone marrow; the blood contains immature cells of the granulocytic series and nucleated red blood cells.
Synonym(s): myelophthisic anemia, myelopathic anemia, leucoerythroblastosis.

leukoerythroblastosis

an anemic condition associated with space-occupying lesions of the bone marrow, marked by a variable number of immature erythroid and myeloid cells in the circulation.
References in periodicals archive ?
Premature labor and leukoerythroblastosis in a newborn with parvovirus B19 infection.
None of our cases showed osteosclerosis and there was absence of significant leukoerythroblastosis as opposed to cases idiopathic myelofibrosis.
It is important to note that there is no evidence of teardrop cells or leukoerythroblastosis as these would be more indicative of PMF.
Absence of splenomegaly, minimal teardrop poikilocytosis and leukoerythroblastosis in the peripheral blood are characteristic.
They emphasized lack of teardrop poikilocytes and leukoerythroblastosis in the peripheral blood with absence of clustered and atypical megakaryocytes and the presence of lymphoid infiltrates in the bone marrow in addition to fibrosis.
All cases showed absence of significant leukoerythroblastosis and teardrop poikilocytosis in the peripheral blood smears and lack of organomegaly.
On the other hand, primary myelofibrosis is characterized by splenomegaly, leukoerythroblastosis, and marrow fibrosis [8].
It can be distinguished from agnogenic myeloid metaplasia by the absence of splenomegaly, teardrop RBCs and leukoerythroblastosis in peripheral blood smears, and from acute megakaryoblastic leukemia by the absence or small percentages of blasts of megakaryocytic origin [17].