A complete blood count documented moderate leukocytosis (white blood cell count [WBC] of 58 600/[micro]L [reference range: 9000-30 000/[micro]L]), while review of a concurrent peripheral blood smear demonstrated leukoerythroblastic
features including 10% to 15% blasts that were large with round to ovoid nuclei, fine chromatin, small distinct nucleoli, and basophilic cytoplasm with occasional cytoplasmic blebs (Figure 1, A through C).
1) showed a leukoerythroblastic
picture with marked polychromasia, large number of circulating nucleated red blood cells and marked poikilocytosis including blister cells, spherocytes and echinocytes, consistent with oxidative hemolysis.
In one case rouleaux formation was seen in peripheral blood while other case showed leukoerythroblastic
This leads to a leukoerythroblastic
anaemia which is most commonly seen in association with metastasis of cancers from the breast, lung, stomach and prostate (Rubins 1983).
The peripheral blood smear presents with a leukoerythroblastic
picture, which includes teardrop RBCs, poikilocytosis, anisocytosis, nucleated red blood cells, and immature myeloid cells.
The peripheral blood smear revealed leukoerythroblastic
Idiopathic primary myelofibrosis is a chronic disorder characterized by bone marrow fibrosis, extramedullary hematopoiesis, and a leukoerythroblastic
blood profile, and it is usually classified as a myeloproliferative syndrome.
anemia in metastatic prostate cancer.
Eichner ER: Spider bite hemolytic anemia: Positive Coombs' test, erythro-phagocytosis, and leukoerythroblastic
The patient was extensively worked up for an infectious etiology of her fevers and anemia and, although the studies were negative for viral or bacterial etiologies, her peripheral blood smear showed a leukoerythroblastic
picture with occasional circulating myeloid precursors, nucleated red blood cells, and teardrop erythrocytes.
In the fibrotic stage, extramedullary hematopoiesis takes place primarily in the spleen and the peripheral blood smear shows a leukoerythroblastic
morphology with teardrop red cells.