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reduction of the number of leukocytes in the blood below about 5000 per mm3. Called also aleukemia, aleukocytosis, and leukocytopenia. adj., adj leukope´nic.
malignant leukopenia (pernicious leukopenia) agranulocytosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


The antithesis of leukocytosis; any situation in which the total number of leukocytes in the circulating blood is less than normal, the lower limit of which is generally regarded as 4000-5000/mm3.
Synonym(s): leukocytopenia
[leuko(cyte) + G. penia, poverty]
Farlex Partner Medical Dictionary © Farlex 2012


Synonym(s): leukopenia, leucocytopenia.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Ghrelin treatment enhanced 30-day survival after CI, significantly accelerated wound healing, mitigated body-weight loss, leukocytopenia, thrombocytopenia, and bone-marrow injury in CI mice.
Key words : Alanine aminotransferase, erythrocytopenia, leukocytopenia, nitrates, sorghum toxicity.
[5] Both interferon and ribavirin are potentially toxic with side effects including anemia, cough and shortness of breath, rash, pruriti s, insomnia, anorexia (ribavirin) [6], flu-like symptoms, nausea, diarrhea, alopecia, leukocytopenia, thyroiditis, thrombocytopenia and psychiatric symptoms (interferon).
This observation further stresses the importance of microscopic clarification of samples with unexplained leukocytopenia.[16] Most of the FP samples exhibited elevated WBC counts, with myeloid precursor cells on microscopic examination, most probably representing reactive conditions.
In humans, SFTS begins with a high fever, marked thrombocytopenia and leukocytopenia, and a high serum viral load, followed by multiorgan dysfunction, which may be a consequence of systemic inflammatory responses and disseminated intravascular coagulation (9,10).
Exclusion criteria included additional diseases in the hip (such as primary osteoarthritis, rheumatoid arthritis), skin lesions around the hip, lumbar disc herniation, diabetes, tuberculosis, chronic infection, coagulation dysfunction, anemia, and leukocytopenia. HIV infection was confirmed by enzyme-linked immunosorbent assays and Western blotting analysis.
Laboratory investigations showed pancytopenia picture with leukocytopenia (white blood cells 3.1x109/L), anaemia (haemoglobin 7.7 g/dL) and thrombocytopenia (platelets 127x109/L).
(4,5) In addition, some patients present with severe baseline thrombocytopenia and leukocytopenia due to hypersplenism that preclude initiation of IFN-based therapy.
None of the six patients had thrombocytopenia and only one had leukocytopenia at baseline, which did not improve with abatacept treatment.
With reference to a case report the recurrence of HCV has been reported to be associated to leukocytopenia (Gruener et al., 2007).
IR assisted in restoration of leukocytopenia after whole mice irradiation with significant reduction of serum TNF-[alpha], IL-1[beta], and IL-6.