leukocyte reduction


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Related to leukocyte reduction: Leukoreduction

leukocyte reduction

Leukocyte depletion, leukodepletion Transfusion medicine Any technique that ↓ WBCs in transfused blood products–eg, RBCs, platelets; LR to < 5 x 108 virtually eliminates nonhemolytic (immunologic) transfusion reactions. See Blood filters, Transfusion effect.

leukocyte reduction

The removal of white blood cells from blood before transfusion to decrease the likelihood of transfusion reactions or infection of the recipient with viral diseases.
See also: reduction
References in periodicals archive ?
Studies also have shown that leukocyte reduction decreases transfusion-associated immune suppression, thereby reducing postoperative morbidity and mortality.
Leukocyte reduction also has been used to reduce alloimmunization and transfusion-transmitted infections (2).
The decision is based on the evidence that leukocyte reduction reduces non-hemolytic febrile reactions, prevents alloimmunization, reduces transmission of cytomegalovirus (CMV), and may reduce transfusion-related suppression of the immune system.

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