Acrodose Platelets are leukocyte reduced
(white blood cells removed), matched for blood type and tested for bacteria using a sensitive culture-based system.
about 80 percent of donated blood is leukocyte reduced.
Blumberg and Heal cite studies showing that surgical patients receiving transfusions that have not been leukocyte reduced have a 50 percent higher rate of post-operative infection.
Blumberg and Heal describe blood transfusion as "temporary organ transplantation," noting that blood that has not been leukocyte reduced has the potential for profound, long-term adverse effects on the immune system's ability to fight disease.
The resulting Acrodose(SM) Platelets are leukocyte reduced
, matched for blood type and tested for bacteria using a sensitive culture-based system, the same type of state-of-the-art systems that are used to test apheresis platelets.
Since a majority of blood transfused in the industrialized world is currently leukocyte reduced
, a filtration approach can swiftly and easily fit into routine operating (cGMP) practice already in use in blood centers around the world.
Donor blood can be leukocyte reduced
by filtration to remove the donor's white blood cells and protect the transfusion recipient.
As a result of the BPAC recommendation and an increase in requests from area hospitals, on June 1, 1999, Coffee Memorial Blood Center began its transition toward supplying 100 percent leukocyte reduced
blood products for all its customers.
We believe pre-storage leukocyte reduced
blood will benefit many patients, particularly those who need repeated transfusions, cancer treatment or major operations," said Dr.
Recently, the UK and Canada joined a growing roster of countries to mandate leukocyte reduced
blood products for all its citizens, while the FDA's Blood Products Advisory Committee voted unanimously to recommend that blood filtration be extended to all US blood products.
It should also speed the acceptance of leukocyte reduced
blood components as the standard of care for all blood transfusion recipients.