leukocyte esterase test

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leu·ko·cyte es·ter·ase test

(LET) (lū'kō-sīt es'tĕr-ās test)
A chemical assay to determine the presence of lysed or intact white blood cells in urine, performed with a dipstick as part of routine urinalysis; serves as an adjunct to microscopic examination of urinary sediment, and used to screen asymptomatic people for urinary tract infection, especially chlamydial urethritis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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A positive leukocyte esterase test results from the presence of white blood cells, either as whole cells or as lysed cells.
The presence of white cells might result in a positive leukocyte esterase test; however, the test is fairly insensitive.
The sensitivity of the leukocyte esterase test compared with the C trachomatis culture was 71.4%, and compared with the N gonorrhoeae culture was 89.6%.
These samples were deemed negative based on the leukocyte esterase test and/or nitrite test, but a culture revealed significant bacteriuria.

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