leukocidin


Also found in: Dictionary, Encyclopedia, Wikipedia.

leukocidin

 [loo″ko-si´din]
1. a substance toxic to leukocytes, killing the cells with or without lysis.
2. a type of exotoxin produced by pathogenic bacteria such as staphylococci or streptococci; it destroys leukocytes and may also damage monocytes and macrophages.

leu·ko·ci·din

(lū'kō-sī'din, lū-kō-sī'din),
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci and manifests a destructive action on leukocytes, with or without lysis of the cells.
[leukocyte + L. caedo, to kill]

leukocidin

/leu·ko·ci·din/ (-si´din) a substance produced by some pathogenic bacteria that is toxic to polymorphonuclear leukocytes (neutrophils).

leukocidin

(1) An antibody which lyses white cells following complement fixation.
(2) A pore-forming cytotoxin produced by certain bacteria.

leu·ko·ci·din

(lū'kō-sī'din)
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci; manifests a destructive action on leukocytes, with or without lysis of the cells.
Synonym(s): leucocidin.
[leukocyte + L. caedo, to kill]

leukocidin

a substance produced by some pathogenic bacteria that is toxic to polymorphonuclear leukocytes (neutrophils).
References in periodicals archive ?
Detection of Panton-valentine leukocidin gene in Staphylococcus aureus by LightCycler PCR: clinical and epidemiological aspects.
Community-acquired methicillin-resistant Staphylococcus aureus: the role of Panton-Valentine leukocidin.
Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia.
Community-acquired methicillin resistance in Staphylococcus aureus: the role of Panton-Valentine leukocidin.
Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin resistant Staphylococcus aureus disease?
CAP and bacteraemia in a healthy young woman caused by mathiclilin-resistant Staphylococcus aureus (MESA) carrying the genes encoding Panton-Valentine leukocidin (PVL).
Infection professors have warned that dangerous Panton-Valentine Leukocidin (PVL) could be the next superbug to strike at the heart of the NHS in the wake of MRSA and Clostridium difficile (C.
Infection professors have warned that dangerous Panton-Valentine Leukocidin, or PVL, could be the next superbug to strike at the heart of the NHS in the wake of MRSA and Clostridium difficile(C.
A majority of causative community-acquired MRSA isolates are associated with genes that encode the virulence factor, Panton-Valentine leukocidin (PVL) toxin (Francis et al, 2005; Naas et al, 2005; Wannet et al, 2005).
CA-MRSA strains are the most likely to produce the Panton-Valentine leukocidin (PVL); furthermore, most CA-MRSA strains have that ability.
The isolates from these infections matched very closely the USA300 strain with staphylococcal cassette chromosome mecIV and were Panton-Valentine leukocidin toxin positive.
Thirty-three people have contracted the deadly Panton-Valentine Leukocidin (PVL) in the region since the first recorded case in 2004.