On an MRI scan, these impairments are visible as white matter lesions (or white matter hyperintensities, sometimes called leukoaraiosis
Homocysteine and the brain in midadult life: Evidence for an increased risk of leukoaraiosis
Microbleed topography, leukoaraiosis
, and cognition in probable Alzheimer disease from the Sunnybrook dementia study.
In 1987, Hachinski introduced the descriptive term "leukoaraiosis
" to define WML without specifying the pathology or aetiology .
Several diseases, including bipolar disorder , Alzheimer , Leukoaraiosis
, and Williams's syndrome , can alter the corpus callosum size in human.
, also known as white matter hyperintensities, is strongly linked to the cerebral small vessel disease, which increases the risk of stroke, cognitive decline, dementia, and infarct progression [1, 2].
We also examined additional previous treatment with antiplatelet agents and presence or absence of leukoaraiosis
on cranial computed tomography (CT) scans on admission.
Head CT showed generalized cerebral volume loss, leukoaraiosis
, and hippocampal sclerosis.
To evaluate for possible confounding factors, an MRI study was made to assess for white matter damage(leukoaraiosis
) and a carotid ultrasound study to assess for carotid plaques and an intima-media thickness (IMT).
Giuffrida et al., "Preserved transcallosal inhibition to transcranial magnetic stimulation in nondemented elderly patients with leukoaraiosis
," BioMed Research International, vol.
Native cranio-cerebral CT image (ischemic lesions, cerebral atherosclerosis, leukoaraiosis
, age-related changes)
The Alberta Stroke Program Early CT (ASPECT) score, that reflects the size of the cerebral ischemia , presence of a hyperdense artery sign and leukoaraiosis
, were assessed by a radiologist.