leukemogen

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leukemogen

[loo-ke´mo-jen]

any substance that produces leukemia. adj., adj leukemogen´ic.

leu·ke·mo·gen

(lū-kē'mō-jen),

Any substance or entity (for example, benzene, ionizing radiation) considered to be a causal factor in the occurrence of leukemia.

Farlex Partner Medical Dictionary © Farlex 2012

leukemogen

Any substance or agent pathogenetically linked to leukaemia; i.e., carcinogen.

leu·ke·mo·gen

(lū-kē'mō-jen)

Any substance or entity considered to be a causal factor in the occurrence of leukemia.
Synonym(s): leukaemogen.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

leu·ke·mo·gen

(lū-kē'mō-jen)

Any substance or entity (e.g., benzene, ionizing radiation) considered to be a causal factor in the occurrence of leukemia.
Synonym(s): leukaemogen.

Medical Dictionary for the Dental Professions © Farlex 2012

References in periodicals archive ?

We evaluated transcriptomic and epigenomic data (epidemiological and clinical) in the range of environmental exposures for three chemicals: a) benzene and other leukemogens (McHale et al.

* Adverse outcome networks (AON) to identify mechanistic commonalties among leukemogens and lifestyle factors (diet and stress) that alter leukemia risks (U.S.

* AONs, once verified for accuracy, are useful in predicting specific hazards [e.g., benzene and other known leukemogens (hematotoxicity) (U.S.

Using bioinformatic approaches to identify pathways targeted by human leukemogens. Int J Environ Res Public Health 9:2479-2503.

The next generation of risk assessment multi-year study--highlights of findings, applications to risk assessment, and future directions

Although experimental data are limited, the disposition and biological activities of [.sup.210]Po in human and animal tissues are consistent with a role as a myelotoxicant and leukemogen. Those adult leukemias epide-miologically associated with chronic exposure to cigarettes or contaminated drinking water have cytogenetic characteristics that are typical of an alpha emitter such as [.sup.210]Po.

[.sup.210]Po is equally plausible as a leukemogen in children.

Occurrence of [.sup.210]Po and biological effects of low-level exposure: the need for research

The workers were considered to have no other substantial workplace exposures; therefore, the possibility of biased potency estimates due to other leukemogens was small.

Other known or suspected leukemogens are present in cigarette smoke, including urethane (30,35), 1,3-butadiene (32,36), radioactive elements (37,38), N-nitrosodi-n-butylamine (30,39), and styrene (30,40); benzene is therefore unlikely to be independently responsible for all smoking-induced leukemia.

The Pliofilm cohort is well suited to minimize the possible confounding effects of other leukemogens because the industrial process did not involve exposure to other potential carcinogens.

The Contribution of Benzene to Smoking-Induced Leukemia

Throwing away radiation dose (i.e., lagging), supposedly because of "dose wasting," is common in some research groups that apparently are not aware that the thrown-away dose may have stimulated the body's natural defenses (7) and thereby protected some members of the population from leukemia induction by other leukemogens. In such cases the dose is not wasted!