leukemia inhibitory factor


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leukemia inhibitory factor

[MIM*159540]
a lymphokine that inhibits the migration of neutrophils.
Farlex Partner Medical Dictionary © Farlex 2012

leu·ke·mi·a in·hib·i·tor·y fac·tor

(lū-kē'mē-ă in-hib'i-tōr-ē fak'tŏr)
A lymphokine that inhibits the migration of neutrophils.
Synonym(s): leukaemia inihibitory factor.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

leukemia inhibitory factor

Abbreviation: LIF
A cytokine that regulates the growth and differentiation of many cells throughout the body, including endothelial cells, fat cells, embryonic stem cells, germ cells, osteoblasts, and peripheral nerve cells.
See also: factor
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Expression of leukemia inhibitory factor (LIF; A) and leukemia inhibitory factor receptor (LIFR; B) mRNAs in the endometrium during the estrous cycle and pregnancy in pigs.
Analysis of leukemia inhibitory factor (LIF) and leukemia inhibitory factor receptor (LIFR) expression in conceptuses from day 12 and day 15 of pregnancy and chorioallantoic tissues during later stages of pregnancy.
In situ hybridization analysis of leukemia inhibitory factor (LIF; A) and leukemia inhibitory factor receptor (LIFR; B) mRNAs in the uterine endometrium during the estrous cycle and pregnancy in pigs.
Leukemia inhibitory factor (LIF) promotes the primordial to primary follicle transition in rat ovaries.
The effects of different concentrations of leukemia inhibitory factor on the development of isolated preantral follicles from fresh and vitrified mouse ovaries.
STAT3 activation in photoreceptors by leukemia inhibitory factor is associated with protection from light damage.
Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation.
Dimitriadis, "Leukemia inhibitory factor enhances endometrial stromal cell decidualization in humans and mice," PLoS ONE, vol.
Berndt et al., "Human chorionic gonadotropin and growth factors at the embryonicendometrial interface control leukemia inhibitory factor (LIF) and interleukin 6 (IL-6) secretion by human endometrial epithelium," Human Reproduction, vol.
The human hepatocyte growth factor (HGF) gene is transcriptionally activated by leukemia inhibitory factor through the Stat binding element.
Leptin-Induced Increase in Leukemia Inhibitory Factor and Its Receptor by Human endometrium is partially mediated by interleukin 1 receptor signaling.
Kojima et al., "Expression of Leukemia Inhibitory Factor in Human Endometrium and Placenta," Biology of Reproduction, 50:882-887, 1994.