leukapheresis


Also found in: Dictionary, Wikipedia.

leukapheresis

 [loo″kah-fĕ-re´sis]
the selective removal of leukocytes from withdrawn blood, which is then retransfused into the donor.

leuk·a·phe·re·sis

(lūk'ă-fĕ-rē'sis),
A procedure, analogous to plasmapheresis, in which leukocytes are removed from the withdrawn blood and the remainder of the blood is retransfused into the donor.
[leuko- + G. aphairesis, a withdrawal]

leukapheresis

/leu·ka·phe·re·sis/ (loo″kah-fĕ-re´sis) the selective separation and removal of leukocytes from withdrawn blood, the remainder of the blood then being retransfused into the donor.

leukapheresis

[lo̅o̅′kəfərē′sis]
Etymology: Gk, leukos + aphairesis, removal
a donation process by which blood is withdrawn from a vein, white blood cells are selectively removed, and the remaining blood is reinfused into the donor. It is a treatment or supportive care measure in patients with leukocytopenia. Compare plasmapheresis, plateletpheresis. See also apheresis.

leukapheresis

Therapeutics The removal of blood to collect specific blood cells; plasma is returned to the body. See Apheresis Transfusion medicine The separation of leukocytes from whole blood with/without platelets with continuous or intermittent return of the RBCs and platelet- and leukocyte-poor plasma to a donor. See Cytapheresis, Hemapheresis, Plateletpheresis.
Leukapheresis types  
'Harvesting' leukapheresis WBCs are donated from healthy subjects to immunocompromised and leukopenic Pts, which may be effective in short-term therapy of acute infections; long-term, Pts become either immunized against the donor antigens or infected with pathogens; 1010 granulocytes are needed for adequate 'coverage' against infections; to maximize the harvest, the donor receives corticosteroids
Reduction leukapheresis WBCs that compromise normal circulation are removed to temporarily relieve Sx of hyperleukemia–> 100 x 109/L; in a typical procedure, ± 6 liters of whole blood are processed to remove 5-10 x 109 WBCs

leuk·a·phe·re·sis

(lū'kă-fĕr-ē'sis)
A procedure, analogous to plasmapheresis, in which leukocytes are removed from the withdrawn blood and the remainder of the blood is retransfused into the donor.
Synonym(s): leucapheresis.
[leuko- + G. aphairesis, a withdrawal]

leukapheresis

the selective removal of leukocytes from withdrawn blood, which are then retransfused into the donor. See also pheresis.
References in periodicals archive ?
On the basis of applications, the apheresis market is segmented into plasmapheresis, plateletpheresis, erythrocytapheresis, leukapheresis, LDL apheresis, and others (photopheresis, lymphapheresis, and extracorporeal immunoadsorption).
It is produced using a small sample from a patient's own tumour and dendritic cells derived from a leukapheresis procedure.
Wright underwent a two-hour process known as leukapheresis, in which his blood was passed through a device to separate out the T cells.
sup][38] Prompt introduction of chemotherapy remains the mainstay of treatment of acute hyperleukocytosis and leukostasis with leukapheresis as an important adjunct.
Diagnostic leukapheresis enables reliable detection of circulating tumor cells of nonmetastatic cancer patients.
Specialist treatment called Leukapheresis was started straight away.
The "Vanishing Counting Bead" Phenomenon: Effect on Absolute CD34+ Cell Counting in PhosphateBuffered Saline-Diluted Leukapheresis Samples.
The successful management of CML during pregnancy by using leukapheresis (5), hydroxyurea, and interferon is noted.
The major limitation of using this technique in large multi-site clinical trials is the need for large blood volume, often requiring leukapheresis.
The drug's cellular immunotherapy is produced by an autologous process called leukapheresis (or apheresis) in which a small number of a patient's immune (mononuclear) cells are removed from the blood over several hours on a specialized cell separator.
The safety evaluation of PROVENGE was based on 601 prostate cancer patients in four randomized clinical trials who underwent at least one leukapheresis.
hematopoietic stem and progenitor cells in leukapheresis product and bone marrow for clinical transplantation: a comparison of three methods.