leukaemia

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leu·ke·mi·a

(lū-kē'mē-ă)
Progressive proliferation of abnormal white blood cells found in hemopoietic tissues, other organs, and usually in the blood in increased numbers. Leukemia is classified by the dominant cell type, and by duration from onset to death, which occurs in acute leukemia within a few months in most cases, and is associated with acute symptoms including severe anemia, hemorrhages, and slight enlargement of lymph nodes or the spleen. The duration of chronic leukemia exceeds 1 year, with a gradual onset of symptoms of anemia or marked enlargement of spleen, liver, or lymph nodes.
Synonym(s): leucaemia, leukaemia.
[leuko- + G. haima, blood]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

leukaemia

one of several forms of cancer in LEUCOCYTES, resulting in an uncontrolled increase of immature white blood cells in body organs and often in the blood itself This leads to increased susceptibility to infection and anaemia, and to the enlargement of the spleen, liver and lymph nodes.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

leu·ke·mi·a

(lū-kē'mē-ă)
Progressive proliferation of abnormal leukocytes found in hemopoietic tissues, other organs, and usually in the blood in increased numbers; classified by dominant cell type, and by duration from onset to death. This occurs in acute leukemia within a few months in most cases, and is associated with acute symptoms including severe anemia, hemorrhages, and slight enlargement of lymph nodes or the spleen. Chronic leukemia lasts over 1 year, with a gradual onset of symptoms of anemia or marked enlargement of spleen, liver, or lymph nodes.
Synonym(s): leucaemia, leukaemia.
[leuko- + G. haima, blood]
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about leukaemia

Q. What is Leukemia? My brother's best friend has been diagnosed with Leukemia. What is it? Is it dangerous? Can you recover from it?

A. Leukemia is the general name for four different types of blood cancers. In people with leukemia, the bone marrow produces abnormal white blood cells. The abnormal cells are leukemia cells. At first, leukemia cells function almost normally. In time, they may crowd out normal white blood cells, red blood cells, and platelets. This makes it hard for blood to do its work. After diagnosis, many people with leukemia do survive and live many good, quality years. The relative five-year survival rate has more than tripled in the past 47 years for patients with leukemia. In 1960-63, when compared to a person without leukemia, a patient had a 14 percent chance of living five years. By 1975-77, the five year relative survival rate had jumped to 35 percent, and in 1996-2003 the overall relative survival rate was nearly 50 percent.

Q. What causes Leukemia? How can one get Leukemia?

A. Not all the causes of leukemia are known. However there are some causes that are suspected. Nowadays as the pollution is increasing and use of chemicals in various parts of life has increased, people who come in contact with toxic chemicals, radiations etc. are at greater risk of developing leukemia, hereditary also plays a role at some extent.

Q. Is Leukemia hereditary? My Grandpa died of Leukemia when he was 50. I am worried that it might be hereditary. Is it?

A. Overall leukemia is not hereditary but there are rare reports of family clusters, that is, more than one case in a family. Therefore, you should consult your Doctor and tell him about your family's medical history.

More discussions about leukaemia
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References in periodicals archive ?
During the study period from October 2013 to September 2014, total 81 blood and bone marrow aspirate samples from leukaemic cases were studied in the Department of Pathology, Gajra Raja Medical College, Gwalior, Madhya Pradesh.
Persistent HPV-B19 tend to occur in immunocompromised patients and manifest as pure cell aplasia and chronic anaemia.2 It also causes severe cytopenia and mimics a leukaemic relapse or therapy-induced cytopenia in patients with haematologic malignancies.3 It is important to consider HPV-B19 infection as a cause of anaemia and suppressed erythropoiesis in children with acute lymphoblastic leukaemia (ALL) receiving ongoing treatment.2
With a view to determining why the disease is so deadly if it relapses, Mullighan and his colleagues collected leukaemic white blood cells from 61 children with ALL as they were diagnosed and after they relapsed.
Effect of bee venom on aromatase expression and activity in leukaemic FLG 29.1 and primary osteoblastic cells.
'Despite the successful stem cell transplant, ultimately in her case the leukaemic cells could not be fully eradicated.'
The importance of aspiration smears lies in recognition of the types of multiple myeloma, as the frequency of a leukaemic blood picture (plasma cell leukaemia) is highest in patients with plasmablastic type and this has an unfavourable prognosis.
In addition, some investigators have indicated that implementing educational and supporting programmes lead to the reduction of anxiety,11 distress,12 behavioral problems13 and promotion of social competency of the healthy siblings of a leukaemic child.12
A case report on B-cell infiltrates inherent in injection sites of a patient with leukaemic mantle cell lymphoma questioned safety of VA-E treatment in lymphomas.
Deletions of chromosome 21 restricted to leukaemic cells of children with Down's syndrome and leukaemia.
The clinical presentation of AML maybe diverse and nonspecific, but is usually directly related to the leukaemic infiltration of the bone marrow, with resultant cell lines depression.