Inclusion criteria were: patients 12 years or older presenting with acute fever associated with two or more of the following; headache, retro-orbital pain, myalgias, arthralgia, rash, abdominal pain, haemorrhagic manifestations, leucopenia
, thrombocytopenia or circulatory collapse in whom tests for dengue fever, NS1 antigen or IgM serology or both were positive.
Otros efectos secundarios son: mielosupresion (anemia, leucopenia
y trombocitopenia), aumento de infecciones virales (citomegalovirus y herpes simple) y por Candida albicans (11).
Las caracteristicas clinicas mas importantes son fiebre, linfadenopatias de predominio cervical, leucopenia
, sintomas respiratorios, artralgias, mialgias y manifestaciones de la piel (ulceras, placas eritematosas y papulas) (1,3).
Although bone marrow suppression with leucopenia
is mentioned as an important side effect of piperacillin/ tazobactam, isolated thrombocytopenia without affection of red cells and leucocytosis has been reported only in few cases.
1%) and mild leucopenia
1 (25%) and patients with age > 15 years had anemia 4 (57.
La mayoria de los pacientes con HRTV presentan fiebre, trombocitopenia, leucopenia
fatiga, anorexia, dolor de cabeza, nauseas, mialgia y artralgia.
Por lo general comienza con un cuadro respiratorio febril, acompanado con tos y poca expectoracion, perdida de peso, anemia y leucopenia
Loss to follow-up, infection and leucopenia
were also frequent reasons for discontinuation of treatment in both groups.
The alterations in the hemogram had only a slight percentage variation in males and females when the total count of leucocytes, number of platelets, counts of segmented neutrophils and atypical lymphocytes and determination of hematocrits were taken into account, excepting total counts of leucocytes where leucopenia
was higher in females.
1987 Importancia da aproximacao de hematologistas e medicos do trabalho em torno da leucopenia
Dengue fever defined as acute febrile illness of last from two to seven days' with symptoms like headache, retro-orbital pain, myalgia, arthralgia, rash, haemorrhagic manifestations, or leucopenia
Laboratory examination showed leucopenia
(89%) and thrombocytopenia (92%).