leukocidin

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leukocidin

 [loo″ko-si´din]
1. a substance toxic to leukocytes, killing the cells with or without lysis.
2. a type of exotoxin produced by pathogenic bacteria such as staphylococci or streptococci; it destroys leukocytes and may also damage monocytes and macrophages.

leu·ko·ci·din

(lū'kō-sī'din, lū-kō-sī'din),
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci and manifests a destructive action on leukocytes, with or without lysis of the cells.
[leukocyte + L. caedo, to kill]

leukocidin

/leu·ko·ci·din/ (-si´din) a substance produced by some pathogenic bacteria that is toxic to polymorphonuclear leukocytes (neutrophils).

leukocidin

(1) An antibody which lyses white cells following complement fixation.
(2) A pore-forming cytotoxin produced by certain bacteria.

leu·ko·ci·din

(lū'kō-sī'din)
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci; manifests a destructive action on leukocytes, with or without lysis of the cells.
Synonym(s): leucocidin.
[leukocyte + L. caedo, to kill]

leukocidin

a substance produced by some pathogenic bacteria that is toxic to polymorphonuclear leukocytes (neutrophils).
References in periodicals archive ?
To further assess the MRSA strains, isolates were characterized by staphylococcal cassette chromosome mec (SCCmec) typing and pulsed field gel electrophoresis (PFGE), and screened for Panton-Valentine leucocidin (PVL), an exotoxin often associated with virulent strains of S.
Linde H, Wagenlehner F, Strommenger B, et al (2005), Healthcare-associated outbreaks and community-acquired infections due to MRSA carrying the Panton-Valentine leucocidin gene in southeastern Germany.
Widespread skin and soft-tissue infections due to two methicillin-resistant Staphylococcus aureus strains harboring the genes for Panton-Valentine leucocidin.
Polyclonal emergence and importation of community-acquired methicillin-resistant Staphylococcus aureus strains harbouring Panton-Valentine leucocidin genes in Belgium.
Methicillin-resistant Staphylococcus aureus containing the Panton-Valentine leucocidin gene in Germany in 2005 and 2006.
A Panton-Valentine leucocidin (PVL)-positive community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strain, another such strain carrying a multiple-drug resistance plasmid, and other more-typical PVL-negative MRSA strains found in Japan.
Emergence of virulent methicillin-resistant Staphylococcus aureus strains carrying Panton-Valentine leucocidin genes in The Netherlands.
Diep BA, Sensabaugh GF, Somboona NS, Carleton HA, Perdreau-Remington E Widespread skin and soft-tissue infections due to two methicillin-resistant Staphylococcus aureus strains harboring the genes for Panton-Valentine leucocidin.