leukocidin

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leukocidin

 [loo″ko-si´din]
1. a substance toxic to leukocytes, killing the cells with or without lysis.
2. a type of exotoxin produced by pathogenic bacteria such as staphylococci or streptococci; it destroys leukocytes and may also damage monocytes and macrophages.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

leu·ko·ci·din

(lū'kō-sī'din, lū-kō-sī'din),
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci and manifests a destructive action on leukocytes, with or without lysis of the cells.
[leukocyte + L. caedo, to kill]
Farlex Partner Medical Dictionary © Farlex 2012

leukocidin

(1) An antibody which lyses white cells following complement fixation.
(2) A pore-forming cytotoxin produced by certain bacteria.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

leu·ko·ci·din

(lū'kō-sī'din)
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci; manifests a destructive action on leukocytes, with or without lysis of the cells.
Synonym(s): leucocidin.
[leukocyte + L. caedo, to kill]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Sriskandan, "Pantone-Valentine leucocidin expression by Staphylococcus aureus exposed to common antibiotics," Infection, vol.
Torres, "Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo," Molecular Microbiology, vol.
To further assess the MRSA strains, isolates were characterized by staphylococcal cassette chromosome mec (SCCmec) typing and pulsed field gel electrophoresis (PFGE), and screened for Panton-Valentine leucocidin (PVL), an exotoxin often associated with virulent strains of S.
CA-MRSA strains are particularly virulent as they often produce a cytotoxic toxin, the Panton-Valentine leucocidin toxin.
Holmes A, Ganner M, McGuane S, et al (2005), Staphylococcus aureus isolates carrying Panton-Valentine leucocidin genes in England and Wales: frequency, characterization, and association with clinical disease.
They produce a toxin called Panton-Valentine leucocidin (PVL) that kills white blood cells, an essential part of the body's immune system defences.
They produce a toxin called Panton-Valentine leucocidin (PVL) which kills white blood cells, an essential part of the body's immune system defences.
necrophorum has both a liposaccharide endotoxin and a heat stable extracellular leucocidin (2,9) these two molecules are responsible for the toxic and inflammatory effects of the bacterium,.
In the same study, Panton-Valentine leucocidin (PVL) was detected among 89.6% (328/366) of all CA-MRSA isolates.