leucine aminopeptidase

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Related to leucine aminopeptidase: leucine aminopeptidase test

leu·cine a·mi·no·pep·ti·dase (LAP),

aminopeptidase (cytosol).

leucine aminopeptidase



A proteolytic enzyme present in the pancreas, liver, and small intestine. Its serum level is elevated in disease of the pancreas, esp. acute pancreatitis, and in obstruction of the common bile duct.


Leu; a naturally occurring amino acid, essential for growth in the young and for nitrogen equilibrium in adults.

leucine aminopeptidase
a digestive enzyme of small intestine enterocytes (brush border).
synthetic form of leucine.
leucine enkephalin
leu-enkephalin; see enkephalin.
natural form of leucine.
leucine zipper
a structured motif found in some DNA binding regulatory proteins formed from a region of α-helix containing at least four leucines, each separated by six amino acids from one another; the leucines align along one edge of the α-helix with one leucine at every second turn of the helix such that the leucine of one protein can interdigitate with the leucines of another protein in a zipper manner.
References in periodicals archive ?
Leucine aminopeptidase a better indicator of carcinoma of liver, biliary tract and Pancreas.
07) with esterase, acid phosphatase, leucine aminopeptidase, and aspartate aminotransferase (Villarroya et al.
Fazlollah Moosavinasab, Masoud Teshfam, Jamshid Ghiasi ghaleh-kandi, BabakTeshfam; Comparison of the Effects of Three Different Types of Probiotics on the Leucine Aminopeptidase (LAP) Activities of the Small Intestine Mucosa of Broiler Chicks
Characterization and partial purification of a leucine aminopeptidase from Fusciola hepatica.
FACS quantitation of leucine aminopeptidase acid phosphatase on tumor-associated macrophages from metastatic and nonmetastatic mouse mammary tumors.
Because of the broad specificity of the substrates, there has been some confusion concerning nomenclature: Serum aminopeptidase is also called leucine aminopeptidase (LAP, the term we use here), alanine aminopeptidase (AAP), aminopeptidase N, aminopeptidase (microsomal), or arylamidase.