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(plural of leptomeninx) the two more delicate components of the meninges: the pia mater and arachnoid considered together; the pia-arachnoid. adj., adj leptomenin´geal.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


(lep'tō-mē'ninks), [TA]
The two delicate layers of the meninges, the arachnoid mater and pia mater (vs. the tough pachymeninx or dura mater), considered together; by this concept, the arachnoid and pia are two parts of a single layer, much like the parietal and visceral layers of a membrane or bursa; although separated by the subarachnoid space they are connected via the arachnoid trabeculae and become continuous where the nerves and filum terminale exit the subarachnoid space (the cerebrospinal fluid-filled space bounded by the leptomeninges).
See also: arachnoid mater, pia mater.
Farlex Partner Medical Dictionary © Farlex 2012


(lep'tō-mĕ-nin'jēz) [TA]
The two delicate layers of the meninges, the arachnoid mater and pia mater considered together.
See also: arachnoid, pia mater
Synonym(s): pia-arachnoid, piarachnoid.
[lepto- + G. mēninx, pl. mēninges, membrane]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Brain; Cerebral cortex (arrow head) and Leptomeninges (black arrow) with a diffuse infiltrate of maligrant cells.
Without an invasive brain biopsy including leptomeninges, it is hard to figure out such a rare DLGNT.
It is often associated with capillary or cavernous hemangiomas affecting primarily but not limited to cutaneous distributions of the trigeminal nerve and rarely venous malformations involving leptomeninges that lead to progressive destruction of the adjunct cerebral cortex.
In our patient, it appeared that the meningeal component of the Cryptococcal infection involved the perivascular spaces at the base of the brain and cerebellar leptomeninges. On magnetic resonance (MR), there was a focal hyperintensity, with abnormal restricted diffusion indicating acute insult.
One possible mechanism is that tumor cells metastasizing to the leptomeninges synthesize and secrete CYFRA 211 at higher levels than their counterparts in the primary tumor or systemic metastasis.
The metastatic spread is seen only in the leptomeninges. MRI; FLAIR (a); FSE/T2WI (b); SE/T1WI after gadolinium administration (c, d); DWI (e); ADC map (f).
Meningiomas are benign tumors of the central nervous system (CNS), which arise from leptomeninges. On gross examination, typical meningioma is lobulated or single, solid mass that is widely attached to the dura mater.
Nakanishi, "Age-dependent responses of glial cells and leptomeninges during systemic inflammation," Neurobiology of Disease, vol.
breast cancer) transformation, genetic change, growth angiogenesis, invasion, transportation, intravasation into blood or lymph vessel, circulation, arrest in 1st capillary bed of CNS organ (brain, leptomeninges), transportation inside brain, passage to arterial circulation, arrest in CNS capillary bed, extravasations, angiogenesis and growth.
She was sent for a brain MRI that revealed metastasis to the brain, which occurs in 10-16% of patients with stage IV breast cancer, arising within the parenchyma or the leptomeninges. (8) The latency between diagnosis of breast cancer and metastasis to the central nervous system (CNS) is two to three years.
There are only a few reports in which colloid cysts are described in other locations such as the fourth ventricle, pituitary gland, leptomeninges, cranial vault, brain-stem, cerebellum and the suprasellar region.1 A report described a case of a colloid cyst of the velum interpositum in a young woman.2 These cysts account for 0.2% to 2% of all intracranial neoplasms.