lepromin test

lep·ro·min test

a test using intradermal injection of a lepromin (for example, Dharmendra or Mitsuda antigen), to classify the stage of leprosy based on the lepromin reaction (for example, Fernandez or Mitsuda reaction); it differentiates tuberculoid leprosy, in which there is a positive delayed reaction at the injection site, from lepromatous leprosy, in which there is no reaction (that is, a negative test result) despite the active malignant Mycobacterium leprae infection; the test is not diagnostic, because normal uninfected people may also react.

lepromin test

[leprō′min]
a skin sensitivity test used to distinguish between the lepromatous and tuberculoid forms of leprosy. The test consists of an intradermal injection of lepromin, which is prepared from heat-sterilized Mycobacterium leprae. The appearance of a palpable nodule in 8 to 10 days is indicative of the tuberculoid form of leprosy. As no nodule appears in the lepromatous form, the test is not diagnostic of leprosy. The test is used only to follow the course of the disease. See also leprosy.

lep·ro·min test

(lep'rō-min test)
An assay in which an intradermal injection of a lepromin is used to classify the stage of leprosy. It differentiates tuberculoid leprosy, in which there is a positive delayed reaction at the injection site, from lepromatous leprosy, in which there is no reaction.

lepromin test

A test for determining the type of HANSEN'S DISEASE suffered by a known leprosy patient. A suspension of dead Mycobacteria leprae is injected into the skin. A positive result-a local reaction-can be seen after 4 weeks. It is negative in LEPROMATOUS LEPROSY and positive in TUBERCULOID LEPROSY.