lepromatous leprosy


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

lep·rom·a·tous lep·ro·sy

a form of leprosy in which nodular cutaneous lesions are infiltrated, have ill-defined borders, and are bacteriologically positive; the lepromin test is negative, that is, the immunologic mechanism of the patient is not responsive to the Mycobacterium leprae infection.

lep·rom·a·tous lep·ro·sy

(lep-rō'mă-tŭs lep'rŏ-sē)
A form of leprosy in which nodular cutaneous lesions are infiltrated, have ill-defined borders, and are bacteriologically positive.

lepromatous leprosy

A severe form of HANSEN'S DISEASE in people with reduced cell-mediated immunity to the causal organism Mycobacterium leprae and widespread dissemination of the organism.
References in periodicals archive ?
Study of rheumatic manifestations and serologic abnormalities in patients with lepromatous leprosy. J Rheumatol.
Androgenic status in patients with lepromatous leprosy. British Journal of Urology 1994;74: 221-4.
A polymorphism in the toll-like receptor 2 is associated with IL-12 production from monocyte in lepromatous leprosy. Cytokine 2002; 20:56-62.
Efficacy of clofazimine in the prophylaxis and suppression of reactive phases of lepromatous leprosy. Int J Lepr Other Mycobact Dis.
Preliminary experiments with gamma interferon indicate it may be useful in treating lepromatous leprosy, a form of Hansen's disease.
Borderline tuberculoid leprosy was responsible for maximum disease load in our patients with 44.8% followed by borderline lepromatous leprosy with 15.8%, lepromatous leprosy & mid-borderline with 11.2% each, tuberculoid type with 10.2%, pure neuritic leprosy with 5%, indeterminate type with 1%.
lepromatosis lepromatous leprosy is a travel-related hazard for travelers to Mexico or other disease-endemic areas.
The slides were then examined by a histopathologist and the reports were interpreted as tuberculoid, borderline tuberculoid, mid borderline, borderline lepromatous and lepromatous leprosy.
Histopathological findings were graded into polar tuberculoid (TT) leprosy, borderline tuberculoid (BT) leprosy, mid-borderline (BB) leprosy, borderline lepromatous (BL) leprosy, and lepromatous leprosy (LL) according to the scale by Ridley and Jopling.
(2) The spectrum of clinical manifestations is illustrated by two polar forms, tuberculoid and lepromatous leprosy, and various intermediate or borderline forms.
Co-existent acquired perforating collagenosis and lepromatous leprosy with erythema nodosum leprosum: Response to treatment.
For the study, researchers compared the micro-RNAs in human skin lesions from two types of leprosy: tuberloid leprosy, a milder infection that is more easily contained, and lepromatous leprosy, which is more serious and causes widespread infection throughout the body.